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Comment
. 2022 Jan 14;375(6577):147-148.
doi: 10.1126/science.abn5428. Epub 2022 Jan 13.

A molecular view of human amyloid-β folds

Michael Willem  1 , Marcus Fändrich  2
Affiliations
Comment

A molecular view of human amyloid-β folds

Michael Willem et al. Science. .

Abstract

Structures of amyloid-β fibrils suggest Alzheimer’s disease–modifying strategies.

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  • Cryo-EM structures of amyloid-β 42 filaments from human brains.
    Yang Y, Arseni D, Zhang W, Huang M, Lövestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M. Yang Y, et al. Science. 2022 Jan 14;375(6577):167-172. doi: 10.1126/science.abm7285. Epub 2022 Jan 13. Science. 2022. PMID: 35025654 Free PMC article.

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