Ultrahigh-efficiency antibacterial and adsorption performance induced by copper-substituted polyoxomolybdate-decorated graphene oxide nanocomposites

Abstract

Given the rise of drug-resistant pathogens and industrial contaminants, the development of efficient and eco-friendly water treatment technologies and materials is highly desirable and urgent. Herein, a multifunctional graphene oxide/chitosan/copper-based polyoxometalate (GO/CS/Cu-POM) nanocomposite (Cu-POM, [Cu(L)₄][Cu(L)₃(H₂O)][Cu(L)(H₂O)][P₂Mo₅O₂₃]·4H₂O, L = pyrazole) was synthesized by the ultrasound-assisted self-assembly strategy. The GO/CS/Cu-POM nanocomposite exhibited potent bactericidal properties against gram-positive/negative bacterial strains Staphylococcus aureus (S. aureus, 99.98%), Escherichia coli (E. coli, 99.99%), and drug-resistant E. coli bacterial strains (kanamycin-resistant E. coli 99.93% and ampicillin-resistant E. coli, 97.94%). Further, the antibacterial performance was strongly dependent on synergistic effect between GO/CS and Cu-POM in GO/CS/Cu-POM. The destruction of bacterial membrane and high levels of oxidative stress induced by GO/CS/Cu-POM played a significant role in the bactericidal process. Furthermore, the GO/CS/Cu-POM nanocomposite also displayed superior performance for removal of methylene blue (MB, 96.86%), gentian violet (GV, 97.77%), basic fuchsin (BF, 96.47%), tetracycline (TC, 78.92%) and norfloxacin (NC, 76.26%). Moreover, the main process of dye removal by GO/CS/Cu-POM was controlled by chemisorption. More importantly, the GO/CS/Cu-POM nanocomposite indicated good biocompatibility to human umbilical vein endothelial cells. Current work provides an effective strategy to design multifunctional POM-based composites for water purification and environmental protection.

Keywords: Antibacterial activity; Dye removal; Graphene oxide; Nanocomposite; Polyoxometalates.