Refining HIV pre-exposure prophylactic agents

Comment

M Teresa Villanueva. Nat Rev Drug Discov. 2022 Feb.

. 2022 Feb;21(2):96.

doi: 10.1038/d41573-022-00014-4.

No abstract available

Keywords: Drug discovery; Infection; Therapeutics; Virology.

Comment on

Long-acting capsid inhibitor protects macaques from repeat SHIV challenges.
Vidal SJ, Bekerman E, Hansen D, Lu B, Wang K, Mwangi J, Rowe W, Campigotto F, Zheng J, Kato D, Chandrashekar A, Barrett J, Patel S, Wan H, Anioke T, Mercado NB, Nkolola JP, Ferguson MJ, Rinaldi WJ, Callebaut C, Blair W, Cihlar T, Geleziunas R, Yant SR, Barouch DH. Vidal SJ, et al. Nature. 2022 Jan;601(7894):612-616. doi: 10.1038/s41586-021-04279-4. Epub 2021 Dec 7. Nature. 2022. PMID: 34875675 Free PMC article.
Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide.
Xue J, Chong H, Zhu Y, Zhang J, Tong L, Lu J, Chen T, Cong Z, Wei Q, He Y. Xue J, et al. Cell. 2022 Jan 6;185(1):131-144.e18. doi: 10.1016/j.cell.2021.11.032. Epub 2021 Dec 16. Cell. 2022. PMID: 34919814

1. Xue, J. et al. Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide. Cell https://doi.org/10.1016/j.cell.2021.11.032 (2021)
1. Vidal, S. J. et al. Long acting capsid inhibitor protects macaques from repeat SHIV challenges. Nature https://doi.org/10.1038/s41586-021-04279-4 (2021)