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. 1978 May 23;518(3):530-4.
doi: 10.1016/0005-2787(78)90171-5.

Pairing properties of the methylester of 5-carboxymethyl uridine in the wobble position of yeast tRNA3Arg

J Weissenbach, G Dirheimer

Pairing properties of the methylester of 5-carboxymethyl uridine in the wobble position of yeast tRNA3Arg

J Weissenbach et al. Biochim Biophys Acta. .

Abstract

At optimum magnesium concentration (10 mM) both yeast tRNA1Arg and tRNA3Arg are able to bind to poly (A,G) and A-G-A in presence of Escherichia coli robisomes. With A-G-G only tRNA1Arg ginds, wherea tRNA3Arg (anticodon mcm5 U-C-U) is not bound. This result means that the methylcarboxymethyl substituant in position 5 of U prevents its wobble with G.

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