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Case Reports
. 2021 Aug 27;7(5Part B):832-834.
doi: 10.1016/j.ijwd.2021.08.010. eCollection 2021 Dec.

Treatment of severe psoriasis during pregnancy and breastfeeding: A therapeutic challenging case

Maria Esposito  1 , Gianluca Calianno  1 , Astrid Lappi  2 , Maria Concetta Fargnoli  1
Affiliations
Case Reports

Treatment of severe psoriasis during pregnancy and breastfeeding: A therapeutic challenging case

Maria Esposito et al. Int J Womens Dermatol. .
No abstract available

Keywords: Anti-TNF; biologics; certolizumab pegol; pregnancy; psoriasis.

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Figures

Fig 1
Fig. 1
(A, D) Intensely erythematous confluent psoriasis plaques involving the trunk and extremities at baseline. (B, E) Consistent clinical improvement after certolizumab treatment at week 8 (32nd week of gestation) and (C, F) week 96.
See this image and copyright information in PMC

References

    1. Clowse ME, Förger F, Hwang C, Thorp J, Dolhain RJ, van Tubergen A, et al. Minimal to no transfer of certolizumab pegol into breast milk: Results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. Ann Rheum Dis. 2017;76(11):1890–1896. - PMC - PubMed
    1. Gottlieb AB, Ryan C, Murase JE. Clinical considerations for the management of psoriasis in women. Int J Womens Dermatol. 2019;5(3):141–150. - PMC - PubMed
    1. Lambe M, Bergstrom AV, Johansson ALV, Weibull CE. Reproductive patterns and maternal and pregnancy outcomes in women with psoriasis-A population-based study. J Am Acad Dermatol. 2020;82(5):1109–1116. - PubMed
    1. Mariette X, Förger F, Abraham B, Flynn AD, Moltó A, Flipo RM, et al. Lack of placental transfer of certolizumab pegol during pregnancy: Results from CRIB, a prospective, postmarketing, pharmacokinetic study. Ann Rheum Dis. 2018;77(2):228–233. - PMC - PubMed
    1. Porter ML, Lockwood SJ, Kimball AB. Update on biologic safety for patients with psoriasis during pregnancy. Int J Womens Dermatol. 2017;3(1):21–25. - PMC - PubMed

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