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Comment
. 2022 Mar;35(2):767-770.
doi: 10.1007/s13577-021-00665-2. Epub 2022 Jan 15.

A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility

Collaborators, Affiliations
Comment

A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility

Shun-Jen Chang et al. Hum Cell. 2022 Mar.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Comment on

  • Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients.
    Nakayama A, Nakatochi M, Kawamura Y, Yamamoto K, Nakaoka H, Shimizu S, Higashino T, Koyama T, Hishida A, Kuriki K, Watanabe M, Shimizu T, Ooyama K, Ooyama H, Nagase M, Hidaka Y, Matsui D, Tamura T, Nishiyama T, Shimanoe C, Katsuura-Kamano S, Takashima N, Shirai Y, Kawaguchi M, Takao M, Sugiyama R, Takada Y, Nakamura T, Nakashima H, Tsunoda M, Danjoh I, Hozawa A, Hosomichi K, Toyoda Y, Kubota Y, Takada T, Suzuki H, Stiburkova B, Major TJ, Merriman TR, Kuriyama N, Mikami H, Takezaki T, Matsuo K, Suzuki S, Hosoya T, Kamatani Y, Kubo M, Ichida K, Wakai K, Inoue I, Okada Y, Shinomiya N, Matsuo H; Japan Gout Genomics Consortium (Japan Gout). Nakayama A, et al. Ann Rheum Dis. 2020 May;79(5):657-665. doi: 10.1136/annrheumdis-2019-216644. Epub 2020 Apr 1. Ann Rheum Dis. 2020. PMID: 32238385 Free PMC article.

References

    1. Nakayama A, Nakatochi M, Kawamura Y, et al. Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Ann Rheum Dis. 2020;79:657–665. doi: 10.1136/annrheumdis-2019-216644. - DOI - PMC - PubMed
    1. Chen CJ, Tseng CC, Yen JH, et al. ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study. Sci Rep. 2018;8:3137. doi: 10.1038/s41598-018-21425-7. - DOI - PMC - PubMed
    1. Nakatochi M, Kanai M, Nakayama A, et al. Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals. Commun Biol. 2019;2:115. doi: 10.1038/s42003-019-0339-0. - DOI - PMC - PubMed
    1. Tin A, Marten J, Halperin Kuhns VL, et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet. 2019;51:1459–1474. doi: 10.1038/s41588-019-0504-x. - DOI - PMC - PubMed
    1. Mattila J, Havula E, Suominen E, et al. Mondo-Mlx mediates organismal sugar sensing through the gli-similar transcription factor sugarbabe. Cell Rep. 2015;13:350–364. doi: 10.1016/j.celrep.2015.08.081. - DOI - PubMed