Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jan 5:2022:1497722.
doi: 10.1155/2022/1497722. eCollection 2022.

Overview of Microvascular Angina Pectoris and Discussion of Traditional Chinese Medicine Intervention

Linghua Yu  1   2 , Xiaoyan Lu  2 , Chenxi Xu  1   2 , Tong Li  1   2 , Yanling Wang  1   2 , Anxiang Liu  1   2 , Yubi Wang  1   2 , Li Chen  1   2 , Huangyu Xu  1   2
Affiliations
Review

Overview of Microvascular Angina Pectoris and Discussion of Traditional Chinese Medicine Intervention

Linghua Yu et al. Evid Based Complement Alternat Med. .

Abstract

Previous research and treatment of coronary heart disease mostly focused on the large epicardial vessels, with limited research on the small endocardial coronary arteries or arterioles that could not be detected by coronary angiography, especially microvascular angina caused by microvascular stenosis or microcirculation dysfunction. Conventional Western medicine therapies have no specific efficacy, but traditional Chinese medicine has significant advantages in this regard. In particular, traditional Chinese medicine of supplementing Qi and activating blood circulation protects the vascular endothelium, relaxes coronary microvessels, reduces myocardial no-reflow after ischemia-reperfusion, increases myocardial hypoxia tolerance, constrains the aggregation of platelet, and increases the rate of blood flow. Moreover, these treatments can significantly improve patients' symptoms through multitarget comprehensive intervention. Here, we analyzed the pathogenesis of microvascular angina pectoris, the treatment status of modern medicine, and the research on the multitarget intervention of traditional Chinese medicine to provide new research ideas for correctly identifying the role of coronary microcirculation in coronary artery disease to solve clinical problems and prevent cardiovascular events.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

Similar articles

See all similar articles

Cited by

References

    1. Li J., Xu H., Shi D. Randomized controlled clinical study of integrated traditional Chinese and Western medicine in coronary heart disease: progress and prospect. Chinese Journal of Integrated Traditional Chinese and Western Medicine . 2017;37(5):517–521.
    1. Filippo C., Camici P. G., Noel B. M. C. Coronary microvascular dysfunction: an update. European Heart Journal . 2014;35(17) - PMC - PubMed
    1. Jacob R., Bachmann T. C., Merete H., et al. Prediction of obstructive coronary artery disease and prognosis in patients with suspected stable angina. European Heart Journal . 2019;40(18):1426–1435. - PubMed
    1. Narbeh M., De Bruyne B., Fearon W. F, MacCarthy P. A. The pathophysiology and clinical course of the normal coronary angina syndrome (cardiac syndrome X) Progress in Cardiovascular Diseases . 2008;50(4) - PubMed
    1. Zhang Y. Mechanism and Intervention of Coronary Slow Flow Microcirculation Disorder . Shangai, China: Naval Military Medical University of the Chinese people’s Liberation Army; 2021.

LinkOut - more resources