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. 2021 Dec 15;13(12):14220-14228.
eCollection 2021.

Personalized nursing improves physical condition and life quality of patients undergoing interventional therapy for liver cancer

Hui Wang  1 , Yu'e Liu  1 , Jing Shen  1 , Tian Du  1
Affiliations

Personalized nursing improves physical condition and life quality of patients undergoing interventional therapy for liver cancer

Hui Wang et al. Am J Transl Res. .

Abstract

Interventional therapy, which can prolong the survival of patients with liver cancer (LC), is an important means to treat the disease. During interventional therapy for LC, it is essential to make a targeted and detailed nursing plan to ameliorate the prognosis. The purpose of this study was to determine the application significance of personalized nursing in patients undergoing interventional therapy for LC. We retrospectively analyzed 136 patients with LC undergoing interventional therapy. Among them, 70 cases receiving personalized nursing were assigned to the observation group (OG), and the remaining 66 cases receiving routine nursing were the control group (CG). After nursing, sleep time of patients in the OG was significantly longer than that in CG. In addition, time to ambulation and hospital stay were shorter in the OG than in the CG. Furthermore, the OG exhibited significantly lower scores of visual analogue scale (VAS) and self-rating anxiety scale (SAS), as well as significantly reduced incidence of adverse reactions than the CG. Compared with the CG, the levels of serum alanine aminotransferase (AST), aspartate aminotransferase (ALT), and total bilirubin (TBIL) were significantly lower in the OG after nursing, while the level of albumin (ALB) was significantly increased. Moreover, patients in the OG showed significantly higher nursing satisfaction and quality of life scores than those in the CG. Therefore, personalized nursing has good prospects for usein interventional therapy for LC.

Keywords: Liver cancer; interventional therapy; personalized nursing; quality of life.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
VAS and SAS scores of patients in the control group and observation group. The VAS (A) and SAS (B) scores of patients in the two groups were significantly lower than those before nursing, and the two scores in the observation group were significantly lower than those of the control group. Note: Paired t-test statistics showed that compared with the VAS score 12 hours after operation or before nursing, *P<0.05; t-test statistics showed that compared with the control group after nursing, *P<0.05.
Figure 2
Figure 2
Changes in liver function indexes of patients in the control group and observation group. There was no significant difference in serum AST (A), ALT (B), ALB (C), or TBIL (D) levels between the two groups before nursing. After nursing, serum AST, ALT, and TBIL levels decreased significantly while ALB increased significantly, and these liver function indexes in the observation group were significantly better than those of the control group. Note: Paired t-test statistics showed that compared with the level before nursing, *P<0.05; t-test statistics showed that compared with the control group after nursing, *P<0.05.
Figure 3
Figure 3
Changes in patients’ quality of life in the control group and observation group. After nursing, the scores of physical function (A), cognitive function (B), role function (C), emotional function (D), and social function (E) of patients in the two groups improved significantly compared with those before nursing, and the scores in the observation group were significantly better than those of the control group. Note: Paired t-test statistics showed that compared with the level before nursing, *P<0.05; t-test statistics showed that compared with the control group after nursing, *P<0.05.
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References

    1. Zhu Y, Tang H, Zhang L, Gong L, Wu G, Ni J, Tang X. Suppression of miR-21-3p enhances TRAIL-mediated apoptosis in liver cancer stem cells by suppressing the PI3K/Akt/Bad cascade via regulating PTEN. Cancer Manag Res. 2019;11:955–968. - PMC - PubMed
    1. Li Z, Lu J, Zeng G, Pang J, Zheng X, Feng J, Zhang J. MiR-129-5p inhibits liver cancer growth by targeting calcium calmodulin-dependent protein kinase IV (CAMK4) Cell Death Dis. 2019;10:789. - PMC - PubMed
    1. Zhao W, Qiu L, Liu H, Xu Y, Zhan M, Zhang W, Xin Y, He X, Yang X, Bai J, Xiao J, Guan Y, Li Q, Chang L, Yi X, Li Y, Chen X, Lu L. Circulating tumor DNA as a potential prognostic and predictive biomarker during interventional therapy of unresectable primary liver cancer. J Gastrointest Oncol. 2020;11:1065–1077. - PMC - PubMed
    1. Si MB, Yan PJ, Hao XY, Du ZY, Tian HW, Yang J, Han CW, Yang KH, Guo TK. Efficacy and safety of radiofrequency ablation versus minimally invasive liver surgery for small hepatocellular carcinoma: a systematic review and meta-analysis. Surg Endosc. 2019;33:2419–2429. - PubMed
    1. Guo L, Ren H, Pu L, Zhu X, Liu Y, Ma X. The prognostic value of inflammation factors in hepatocellular carcinoma patients with hepatic artery interventional treatments: a retrospective study. Cancer Manag Res. 2020;12:7173–7188. - PMC - PubMed

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