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Randomized Controlled Trial
. 2022 Jan 5:2022:3170947.
doi: 10.1155/2022/3170947. eCollection 2022.

Effects of Caffeine Intake on Cardiopulmonary Variables and QT Interval after a Moderate-Intensity Aerobic Exercise in Healthy Adults: A Randomized Controlled Trial

JaeHo Yu  1 , Jeong-Hun Lim  1 , Sang-Woo Seo  1 , DongYeop Lee  1 , JiHeon Hong  1 , JinSeop Kim  1 , SeongGil Kim  1 , Daekook M Nekar  1 , HyeYun Kang  1
Affiliations
Randomized Controlled Trial

Effects of Caffeine Intake on Cardiopulmonary Variables and QT Interval after a Moderate-Intensity Aerobic Exercise in Healthy Adults: A Randomized Controlled Trial

JaeHo Yu et al. Biomed Res Int. .

Retraction in

Abstract

Caffeine is considered a widely consumed natural and legal psychoactive stimulant with several effects on the body. The present study attempted to investigate the effects of caffeine consumed before and after a physical exercise on cardiovascular and cardiorespiratory functions in healthy adults. 36 healthy adult males were recruited and randomly allocated to one of the three (3) groups: group I (exercise without caffeine consumption), group II (caffeine beverage intake before exercise), and group III (caffeine beverage intake immediately after exercise). The heart rate (HR), QTc interval, blood pressure (BP), respiratory rate (RR), oxygen consumption (VO₂), and carbon dioxide emission (VCO₂) were measured at 0, 5, 10, and 15 min after the exercise. We observed a significant difference in all measured outcomes during the different recovery times in all the groups (p < 0.05). HR, RR, SBP, VO2, and VCO2 gradually decreased with time, DBP contrarily increased with time, and the QTc showed an irregular pattern. We can affirm that ingestion of caffeine before and after moderate aerobic exercise slows down the parasympathetic stimulation, heart rate recovery, and the recovery of HR and QTc with no major effects on BP, RR, VO₂, and VCO₂ in healthy adult men.

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Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this paper.

Figures

Figure 1
Figure 1
CPX machine.
Figure 2
Figure 2
The attached location of ECG: (a) anterior and (b) lateral side. (1) RA, (2) LA, (3) RL, (4) LL, (5) V1, (6) V2, (7) V3, (8) V4, (9) V5, and (10) V6.
Figure 3
Figure 3
Gas analyzer, blood pressure meter, and ECG on CPX.
Figure 4
Figure 4
Research block diagram.
Figure 5
Figure 5
The change of HR, RR, BP, VCO2, VCO2, and QTc between groups over recovery time.
See this image and copyright information in PMC

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