Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jul-Sep;65(3):255-258.
doi: 10.22336/rjo.2021.50.

Optical Coherence Tomography and ImageJ Software for objective assessment of optical density of anterior chamber iris cyst

Affiliations
Case Reports

Optical Coherence Tomography and ImageJ Software for objective assessment of optical density of anterior chamber iris cyst

Avadhesh Oli et al. Rom J Ophthalmol. 2021 Jul-Sep.

Abstract

Aim: To report the optical characteristics of the fluid in an anterior chamber iris cyst. Method: A 26-year-old male presented with blurring of vision in his right eye for two months, without any other associated ocular complaints. His visual acuity was 6/ 9 on Snellen's chart. On slit lamp examination, a small translucent pigmented cyst was noted inferiorly in the anterior chamber, struck on to the cornea at 6 o'clock periphery, without any feeder vessel. Anterior segment optical coherence tomography (OCT) revealed a cystic lesion with hyperreflective walls and hypo reflective lumen attached to the cornea, compressing the endothelium. Results: The optical density (OD) of the cyst fluid was determined using ImageJ, an open code Java-based image processing software. The OD of cyst fluid was found comparable to the anterior chamber fluid. Conclusion: Ultrasound biomicroscopy (UBM) and OCT are useful tools for the diagnosis of cystic lesions of the anterior segment. The innovative use of an OCT image and the ImageJ software to determine the optical density of the iris cyst may aid in the diagnosis and follow-up of such cases.

Keywords: ImageJ for iris cyst; Optical Coherence Tomography; iris cyst; optical density.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
A, B Slit-lamp photograph of the right eye showing a pigmented translucent cyst in the anterior chamber, struck to the cornea at 6 o’clock; C, D OCT scan showing a cystic lesion in the anterior chamber with hyperreflective walls and clear hypo reflective lumen attached to the cornea. The optical density on ImageJ software is comparable to anterior chamber fluid

References

    1. Shields JA. Primary cysts of the iris. Transactions of the American Ophthalmological Society. 1981;79:771–809. - PMC - PubMed
    1. Georgalas I, Petrou P, Papaconstantinou D, Brouzas D, Koutsandrea C, Kanakis M. Iris cysts: A comprehensive review on diagnosis and treatment. Surv Ophthalmol. 2018;63(3):347–364. - PubMed
    1. Rotsos T, Bagikos G, Christou S, et al. Free-Floating Iris Pigmented Epithelial Cyst in the Anterior Chamber. Case reports in Ophthalmological Medicine. 2016;2016:4731037. - PMC - PubMed
    1. Neudorfer M, Weinberg A, Loewenstein A, Barak A. Differential optical density of subretinal spaces. Investigative Ophthalmology & Visual Science. 2012;53(6):3104–3110. - PubMed
    1. Ahlers C, Golbaz I, Einwallner E, et al. Identification of optical density ratios in subretinal fluid as a clinically relevant biomarker in exudative macular disease. Investigative Ophthalmology & Visual Science. 2009;50(7):3417–3424. - PubMed

Publication types

LinkOut - more resources