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Comment
. 2022 May;48(5):624-625.
doi: 10.1007/s00134-022-06621-4. Epub 2022 Jan 17.

De-adoption of chlorhexidine oral care and ICU mortality

Stijn Blot  1   2 , Mieke Deschepper  3 , Sonia Labeau  4
Affiliations
Comment

De-adoption of chlorhexidine oral care and ICU mortality

Stijn Blot et al. Intensive Care Med. 2022 May.
No abstract available

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References

    1. Deschepper M, Waegeman W, Eeckloo K et al (2018) Effects of chlorhexidine gluconate oral care on hospital mortality: a hospital-wide, observational cohort study. Intensive Care Med 44:1017–1026. https://doi.org/10.1007/s00134-018-5171-3 - DOI - PubMed - PMC
    1. Dale CM, Rose L, Carbone S et al (2021) Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge cluster-randomized controlled trial. Intensive Care Med 47:1295–1302. https://doi.org/10.1007/s00134-021-06475-2 - DOI - PubMed - PMC
    1. Blot S (2021) Antiseptic mouthwash, the nitrate-nitrite-nitric oxide pathway, and hospital mortality: a hypothesis generating review. Intensive Care Med 47:28–38. https://doi.org/10.1007/s00134-020-06276-z - DOI - PubMed
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    1. Montenegro MF, Sundqvist ML, Larsen FJ et al (2017) Blood pressure-lowering effect of orally ingested nitrite is abolished by a proton pump inhibitor. Hypertension 69:23–31. https://doi.org/10.1161/HYPERTENSIONAHA.116.08081 - DOI - PubMed

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