Preservation of the substantia nigra and locus coeruleus in a patient receiving levodopa (2 kg) plus decarboxylase inhibitor over a four-year period
- PMID: 3504233
- DOI: 10.1002/mds.870010109
Preservation of the substantia nigra and locus coeruleus in a patient receiving levodopa (2 kg) plus decarboxylase inhibitor over a four-year period
Abstract
A 72-year-old hypertensive man developed parkinsonism and was treated with Sinemet for 4 years but then died of a bronchial carcinoma. Necropsy revealed cerebrovascular disease and amyloid angiopathy. The substantia nigra and locus coeruleus were normal on light microscopy.
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