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. 2022 Mar;18(9):1115-1132.
doi: 10.2217/fon-2021-0635. Epub 2022 Jan 19.

Patient preferences for breast cancer treatments: a discrete choice experiment in France, Ireland, Poland and Spain

Eugena Stamuli  1 , Sorcha Corry  2 , Derek Ross  3 , Thomais Konstantopoulou  4 ; Advisory board participants from France:, Advisory board participants from Ireland:, Advisory board participants from Poland:, Advisory board participants from Spain:
Collaborators, Affiliations
Free article

Patient preferences for breast cancer treatments: a discrete choice experiment in France, Ireland, Poland and Spain

Eugena Stamuli et al. Future Oncol. 2022 Mar.
Free article

Abstract

Aim: To understand breast cancer patients' trade-offs when choosing treatments and to identify the most important treatment attributes which drive decisions. Materials & methods: A discrete choice experiment was conducted in France, Ireland, Poland and Spain. Progression-free survival, febrile neutropenia, pain, functional well-being and out-of-pocket payment were the treatment attributes. Results: 371 patients were willing to pay €6896 per year for 1 additional year of progression-free survival, €17,288 per year for perfect functional well-being and €15,138 for one pain-free year. Patients are willing to trade off progression-free survival months for better functional abilities and less pain. Conclusion: Patient preferences should be considered by regulatory agencies, reimbursement bodies, payors and clinicians for best treatment choices for the individuals.

Keywords: Europe; breast cancer; discrete choice experiment; trade-offs; treatment characteristics.

Plain language summary

The authors wanted to explore what breast cancer patients want the most from their cancer treatments. For this purpose, their preferences were collected in four European countries via a discrete choice experiment. The study showed that patients prefer treatments that improve their ability to function well in their daily lives and reduce their levels of pain. Patients' preferences for treatment outcomes might differ from those of the treating clinicians or regulators. Hence, these aspects can be discussed with their clinicians to make a joint decision on the choice of treatments.

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