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Review
. 2022 Jan 3:12:796824.
doi: 10.3389/fphar.2021.796824. eCollection 2021.

Production of Bovine Colostrum for Human Consumption to Improve Health

Merve Kaplan  1 , Ayşenur Arslan  1 , Hatice Duman  1 , Melda Karyelioğlu  1 , Barış Baydemir  2 , Bilgetekin Burak Günar  3 , Merve Alkan  1   4 , Ayşe Bayraktar  1   4 , Halil İbrahim Tosun  4 , Melih Ertürk  4 , Günay Eskici  2 , Rebbeca M Duar  5 , Bethany M Henrick  5   6 , Steven A Frese  7 , Sercan Karav  1
Affiliations
Review

Production of Bovine Colostrum for Human Consumption to Improve Health

Merve Kaplan et al. Front Pharmacol. .

Abstract

Colostrum contains all essential nutrients for the neonate during the first days of life, with impacts that continue far beyond these first days. Bovine colostrum has been used for human consumption due to the high concentrations of bioactive proteins, vitamins, minerals, growth factors, as well as free and conjugated oligosaccharides. Processes involved in the preparation of bovine colostrum for human consumption play a pivotal role in preserving and maintaining the activity of the bioactive molecules. As bovine colostrum is a multifunctional food that offers a myriad of benefits for human health, assessing the main processes used in preparing it with both advantages and disadvantages is a crucial point to discuss. We discuss major processes effects for colostrum production on the nutritional value, some advanced technologies to preserve processed bovine colostrum and the end-product forms consumed by humans whether as dairy products or dietary supplements.

Keywords: bovine colostrum; drying methods; human consumption; immunoglobulins; liposomal technology; nanotechnology; thermal processing.

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Conflict of interest statement

ME, MA, HIT and AB are employed by the company Uluova Dairy. BMH and RMD are employed by the company Evolve Biosystems, Inc, United States. SK has received funding from Uluova Süt Ticaret A.S (Uluova Milk Trading Co.) and Evolve Biosystems, Inc, United States. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Drying methods.
See this image and copyright information in PMC

References

    1. Abd El-Fattah A. M., Abd Rabo F. H. R., El-Dieb S. M., Satar El-Kashef H. A. (2014). Preservation Methods of buffalo and Bovine Colostrum as a Source of Bioactive Components. Int. Dairy J. 39, 24–27. 10.1016/j.idairyj.2014.04.008 - DOI
    1. Abdel-Ghany A. S., Zaki D. A. (2018). Production of Novel Functional Yoghurt Fortified with Bovine Colostrum and Date Syrup for Children. Alexandria Sci. Exchange J. 39, 651–662. 10.21608/asejaiqjsae.2018.20475 - DOI
    1. Ahmadi M. (2011). Benefits of Bovine Colostrum in Nutraceutical Products. J. Agroalimentary Process. Technol. 17, 42–45.
    1. Alexieva B., Markova T., Nikolova E. (2011). Bovine Colostrum – the Promising Nutraceutical. Czech J. Food Sci. 22, 73–79. 10.17221/3409-CJFS - DOI
    1. Amelia I., Barbano D. M. (2013). Production of an 18% Protein Liquid Micellar Casein Concentrate with a Long Refrigerated Shelf Life. J. Dairy Sci. 96, 3340–3349. 10.3168/jds.2012-6033 - DOI - PubMed