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Review
. 2022 Jan 3:8:814976.
doi: 10.3389/fmed.2021.814976. eCollection 2021.

Exercise-Induced Bronchoconstriction in Children

Angela Klain  1 , Cristiana Indolfi  1 , Giulio Dinardo  1 , Marcella Contieri  1 , Fabio Decimo  1 , Michele Miraglia Del Giudice  1
Affiliations
Review

Exercise-Induced Bronchoconstriction in Children

Angela Klain et al. Front Med (Lausanne). .

Abstract

Exercise-induced bronchoconstriction (EIB) is a transient airflow obstruction, typically 5-15 min after physical activity. The pathophysiology of EIB is related to the thermal and osmotic changes of the bronchial mucosa, which cause the release of mediators and the development of bronchoconstriction in the airways. EIB in children often causes an important limitation to physical activities and sports. However, by taking appropriate precautions and through adequate pharmacological control of the condition, routine exercise is extremely safe in children. This review aims to raise awareness of EIB by proposing an update, based on the latest studies, on pathological mechanisms, diagnosis, and therapeutic approaches in children.

Keywords: asthma; atopy; children; exercise induced asthma; exercise-induced bronchoconstriction.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Pathophysiology and mechanisms underlying exercise-induced bronchoconstriction.
Figure 2
Figure 2
EIB flow chart in children, according to ATS.
See this image and copyright information in PMC

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