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. 2022 Jan 8;9(1):16.
doi: 10.3390/jcdd9010016.

News from the Cold Chamber: Clinical Experiences of POLARx versus Arctic Front Advance for Single-Shot Pulmonary Vein Isolation

Denise Guckel  1 , Philipp Lucas  1 , Khuraman Isgandarova  1 , Mustapha El Hamriti  1 , Leonard Bergau  1 , Thomas Fink  1 , Vanessa Sciacca  1 , Guram Imnadze  1 , Martin Braun  1 , Moneeb Khalaph  1 , Georg Nölker  1   2 , Philipp Sommer  1 , Christian Sohns  1
Affiliations

News from the Cold Chamber: Clinical Experiences of POLARx versus Arctic Front Advance for Single-Shot Pulmonary Vein Isolation

Denise Guckel et al. J Cardiovasc Dev Dis. .

Abstract

Cryoballoon (CB)-guided pulmonary vein isolation (PVI) represents a cornerstone in the treatment of atrial fibrillation (AF). Recently, a novel balloon-guided single shot device (POLARx, Boston Scientific) was designed. Our study aimed to compare the efficacy, safety and characteristics of the novel CB system with the established one (Arctic Front Advance (Pro), AFA, Medtronic). A total number of 596 patients undergoing CB-guided ablation for AF were included. 65 patients (65.0 ± 11.6, 31% female) undergoing PVI with the POLARx were compared to a cohort of 531 consecutive patients (63.0 ± 27.9, 25% female) treated with AFA. Acute PVI was achieved in all patients (n = 596, 100%). Total procedure duration (POLARx 113.3 ± 23.2 min, AFA 100.9 ± 21.3 min; p < 0.001) and fluoroscopy time (POLARx 10.5 ± 5.9 min, AFA 4.8 ± 3.6 min; p < 0.001) were significantly longer in the POLARx group. The POLARx balloon achieved significantly lower nadir temperatures (POLARx -57.7 ± 0.9 °C, AFA -45.1 ± 2.6 °C; p < 0.001) and a significantly higher percentage of pulmonary veins successfully isolated with the first freeze (p = 0.027 *). One major complication occurred in the POLARx (2%) and three (1%) in the AFA group. Both ablation systems are comparably safe and effective. AF ablation utilizing the POLARx system is associated with longer procedure and fluoroscopy times as well as lower nadir temperatures.

Keywords: atrial fibrillation; catheter ablation; cryoballoon; single-shot ablation devices.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Novel diaphragm movement sensor (DMS). (A) The novel diaphragm movement sensor is placed on an electrode below the right-sided costal cartilage. (B) Section of the SMARTFREEZE Cryoablation Console surface with visualization of the DMS during pacing of the right-sided phrenic nerve and isolation of the right inferior pulmonary vein.
Figure 2
Figure 2
Fluoroscopic example of LSPV freezing. (A) LSPV freezing with the POLARx compared to the (B) AFA CBA catheter. CBA, cryoballoon ablation.
See this image and copyright information in PMC

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