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. 2021 Dec 24;10(1):23.
doi: 10.3390/healthcare10010023.

Perioperative Outcomes in COVID-19 Obstetric Patients Undergoing Spinal Anesthesia for Cesarean Section: A Prospective Observational Study

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Perioperative Outcomes in COVID-19 Obstetric Patients Undergoing Spinal Anesthesia for Cesarean Section: A Prospective Observational Study

Omar Ababneh et al. Healthcare (Basel). .

Abstract

Coronavirus disease 2019 (COVID-19) adds more challenges to the perioperative management of parturients. The aim of this study is to examine perioperative adverse events and hemodynamic stability among COVID-19 positive parturients undergoing spinal anesthesia. This prospective observational investigation was conducted at a tertiary teaching hospital in Jordan between January and June 2021, during which 31 COVID-19 positive parturients were identified. Each COVID-19 positive parturient was matched with a COVID-19 negative parturient who received anesthesia under similar operating conditions as a control group. Of the 31 COVID-19 patients, 22 (71%) were otherwise medically free, 8 (25.8%) were emergency cesarean sections. The sensory level of spinal block after 10 min was T8 (T6-T10) among COVID-19 positive group, compared to T4 (T4-T6) among control group (p = 0.001). There were no significant differences in heart rate, SBP, DBP, and MAP intraoperatively (p > 0.05). Twelve (36.4%) neonates born to COVID-19 positive patients were admitted to NICU, compared to four (11.8%) among control group (p = 0.018). There was no statistically significant difference in postoperative complications. In conclusion, spinal anesthesia is considered a safe anesthetic technique in COVID-19 parturients, and therefore it is the anesthetic method of choice for cesarean deliveries among COVID-19 patients.

Keywords: COVID-19; cesarean section; neuraxial anesthesia; pregnancy.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Vital signs in COVID-19 positive patients. The x-axis represents the timing of vital signs obtainment. Intraoperatively, vital signs were documented every 5 min until transfer to the PACU. The y-axis represents the value of vital signs, measured in beats per minute (BPM) for heart rate, mmHg for systolic, diastolic, and mean blood pressure. PACU: post anesthesia care unit. Vital signs are presented along with comparison with COVID-19 negative group in Supplementary Table S1.
Figure 2
Figure 2
Vital signs in COVID-19 negative patients. The x-axis represents the timing of vital signs obtainment. Intraoperatively, vital signs were documented every 5 min until transfer to the PACU. The y-axis represents the value of vital signs, measured in beats per minute (BPM) for heart rate, mmHg for systolic, diastolic, and mean blood pressure. PACU: post anesthesia care unit. Vital signs are presented along with comparison with COVID-19 positive group in Supplementary Table S1.
Figure 3
Figure 3
A comparison in oxygen (O2) saturation between COVID-19 positive and negative patients. The x-axis represents the timing of O2 saturation measurement. Intraoperatively, O2 saturation was documented every 5 min until transfer to the PACU. The y-axis represents the O2 saturation in percentage (%). PACU: post anesthesia care unit. Vital signs are presented along with comparison with COVID-19 positive group in Supplementary Table S1.

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References

    1. Weiniger C.F. What’s new in obstetric anesthesia in 2018? Int. J. Obstet. Anesth. 2020;42:99–108. doi: 10.1016/j.ijoa.2020.03.002. - DOI - PubMed
    1. Zambrano L.D., Ellington S., Strid P., Galang R.R., Oduyebo T., Tong V.T., Woodworth K.R., Nahabedian J.F., III, Azziz-Baumgartner E., Gilboa S.M., et al. Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status—United States, 22 January–3 October 2020. MMWR Morb. Mortal. Wkly. Rep. 2020;69:1641–1647. doi: 10.15585/mmwr.mm6944e3. - DOI - PMC - PubMed
    1. Villar J., Ariff S., Gunier R.B., Thiruvengadam R., Rauch S., Kholin A., Roggero P., Prefumo F., Do Vale M.S., Cardona-Perez J.A., et al. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women with and without COVID-19 Infection: The INTERCOVID Multinational Cohort Study. JAMA Pediatr. 2021;175:817–826. doi: 10.1001/jamapediatrics.2021.1050. - DOI - PMC - PubMed
    1. Chen R., Zhang Y., Huang L., Cheng B.-H., Xia Z.-Y., Meng Q.-T. Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: A case series of 17 patients. Can. J. Anaesth. 2020;67:655–663. doi: 10.1007/s12630-020-01630-7. - DOI - PMC - PubMed
    1. Birnbach D.J., Bateman B.T. Obstetric Anesthesia: Leading the Way in Patient Safety. Obstet. Gynecol. Clin. N. Am. 2019;46:329–337. doi: 10.1016/j.ogc.2019.01.015. - DOI - PubMed