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. 2022 Jan 13;11(2):379.
doi: 10.3390/jcm11020379.

HCV Genotype Has No Influence on the Incidence of Diabetes-EpiTer Multicentre Study

Paweł Rajewski  1 , Dorota Zarębska-Michaluk  2 , Ewa Janczewska  3 , Andrzej Gietka  4 , Włodzimierz Mazur  5 , Magdalena Tudrujek-Zdunek  6 , Krzysztof Tomasiewicz  6 , Teresa Belica-Wdowik  7 , Barbara Baka-Ćwierz  7 , Dorota Dybowska  8 , Waldemar Halota  8 , Beata Lorenc  9 , Marek Sitko  10 , Aleksander Garlicki  10 , Hanna Berak  11 , Andrzej Horban  11 , Iwona Orłowska  12 , Krzysztof Simon  12 , Łukasz Socha  13 , Marta Wawrzynowicz-Syczewska  13 , Jerzy Jaroszewicz  14 , Zbigniew Deroń  15 , Agnieszka Czauż-Andrzejuk  16 , Jolanta Citko  17 , Rafał Krygier  18 , Anna Piekarska  19 , Łukasz Laurans  13   20 , Witold Dobracki  21 , Jolanta Białkowska  22 , Olga Tronina  23 , Magdalena Wietlicka-Piszcz  24 , Małgorzata Pawłowska  8 , Robert Flisiak  16
Affiliations

HCV Genotype Has No Influence on the Incidence of Diabetes-EpiTer Multicentre Study

Paweł Rajewski et al. J Clin Med. .

Abstract

HCV infection is one of the main reasons for liver cirrhosis and hepatocellular carcinoma. In recent years, one finds more and more extrahepatic manifestations of HCV infection, including its possible influence on the development of diabetes. In the presented work, one finds the frequency analysis of the incidence of diabetes among 2898 HCV infected patients treated in Poland, and the assessment of their relevance to the HCV genotype and the progression of fibrosis. The results indicate that the hepatitis C infection seems to be a risk factor for diabetes in persons with more advanced liver fibrosis, for older people, and for the male gender. Thus, one found no differences regarding the frequency of its incidence depending on HCV genotype, including genotype 3.

Keywords: diabetes; genotype HCV; hepatitis C virus.

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Conflict of interest statement

The authors declare no conflict of interest.

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