Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan 12;12(1):97.
doi: 10.3390/jpm12010097.

Prevalence of Chronic Kidney Disease and Variation of Its Risk Factors by the Regions in Okayama Prefecture

Affiliations

Prevalence of Chronic Kidney Disease and Variation of Its Risk Factors by the Regions in Okayama Prefecture

Ryoko Umebayashi et al. J Pers Med. .

Abstract

Objective: The prevention of chronic kidney disease (CKD) progression is an important issue from health and financial perspectives. We conducted a single-year cross-sectional study to clarify the prevalence of CKD and its risk factors along with variations in these factors among five medical regions in Okayama Prefecture, Japan.

Methods and results: Data concerning the renal function and proteinuria as well as other CKD risk factors were obtained from the database of the Japanese National Health Insurance. The proportion of CKD patients at an increased risk of progression to end-stage renal disease (ESRD), classified as orange and red on the CKD heatmap, ranged from 6-9% and did not vary significantly by the regions. However, the causes of the increased severity differed between regions where renal dysfunction was predominant and regions where there were many patients with proteinuria. CKD risk factors, such as diabetes mellitus, hypertension, hyper low-density lipoprotein-cholesterolemia, obesity, smoking and lack of exercise, also differed among these regions, suggesting that different regions need tailored interventions that suit the characteristics of the region, such as an increased health checkup ratio, dietary guidance and promotion of exercise opportunities.

Conclusions: Approximately 6-9% of people are at an increased risk of developing ESRD (orange or red on a CKD heatmap) among the population with National Health Insurance in Okayama Prefecture. The underlying health problems that cause CKD may differ among the regions. Thus, it is necessary to consider intervention methods for preventing CKD progression that are tailored to each region's health problems.

Keywords: chronic kidney disease; medical checkup; risk factor.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
CKD heatmaps of each region. The left column shows the actual number of people in each category by the renal function and proteinuria, and the right column shows the number and proportion of people classified by risk of ESRD. ESRD: end-stage renal disease.

References

    1. Hsu C.Y., Vittinghoff E., Lin F., Shlipak M.G. The incidence of end-stage renal disease is increasing faster than the prevalence of chronic renal insufficiency. Ann. Intern. Med. 2004;141:95–101. doi: 10.7326/0003-4819-141-2-200407200-00007. - DOI - PubMed
    1. Japan Nephrology’s Special issue: Clinical practice guidebook for diagnosis and treatment of chronic kidney disease 2012. Nihon Jinzo Gakkai Shi. 2012;54:1034–1191. - PubMed
    1. Nitta K., Masakane I., Hanafusa N., Taniguchi M., Hasegawa T., Nakai S., Goto S., Wada A., Hamano T., Hosino J., et al. Annual dialysis data report 2017, JSDT Renal Data Registry. Ren. Replace. Ther. 2019;5:53. doi: 10.1186/s41100-019-0248-1. - DOI
    1. Levey A.S., de Jong P.E., Coresh J., El Nahas M., Astor B.C., Matsushita K., Gansevoort R.T., Kasiske B.L., Eckardt K.-U. The definition, classification, and prognosis of chronic kidney disease: A KDIGO Controversies Conference report. Kidney Int. 2011;80:17–28. doi: 10.1038/ki.2010.483. - DOI - PubMed
    1. Kakio Y., Uchida H.A., Takeuchi H., Okuyama Y., Umebayashi R., Watatani H., Maeshima Y., Sugiyama H., Wada J. Report of health checkup system for chronic kidney disease in general population in Okayama city: Effect of health guidance intervention on chronic kidney disease outcome. Int. J. Nephrol. Renovasc. Dis. 2019;12:143–152. doi: 10.2147/IJNRD.S198781. - DOI - PMC - PubMed

LinkOut - more resources