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Review
. 2022 Jan 6;58(1):84.
doi: 10.3390/medicina58010084.

Current Status and Future Therapeutic Options for Fecal Microbiota Transplantation

Sergii Tkach  1 , Andrii Dorofeyev  2 , Iurii Kuzenko  1 , Nadiya Boyko  3 , Tetyana Falalyeyeva  4   5 , Luigi Boccuto  6 , Emidio Scarpellini  7 , Nazarii Kobyliak  5   8 , Ludovico Abenavoli  9
Affiliations
Review

Current Status and Future Therapeutic Options for Fecal Microbiota Transplantation

Sergii Tkach et al. Medicina (Kaunas). .

Abstract

The intestinal microbiota plays an important role in maintaining human health, and its alteration is now associated with the development of various gastrointestinal (ulcerative colitis, irritable bowel syndrome, constipation, etc.) and extraintestinal diseases, such as cancer, metabolic syndrome, neuropsychiatric diseases. In this context, it is not surprising that gut microbiota modification methods may constitute a therapy whose potential has not yet been fully investigated. In this regard, the most interesting method is thought to be fecal microbiota transplantation, which consists of the simultaneous replacement of the intestinal microbiota of a sick recipient with fecal material from a healthy donor. This review summarizes the most interesting findings on the application of fecal microbiota transplantation in gastrointestinal and extraintestinal pathologies.

Keywords: gastrointestinal diseases; health; liver diseases; metabolism.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Worldwide distribution of FMT research across regions.
Figure 2
Figure 2
List of countries with the most active contributions in FMT investigation.
See this image and copyright information in PMC

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