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Comment
. 2022 Mar;91(4):730-732.
doi: 10.1038/s41390-022-01937-9. Epub 2022 Jan 20.

Looking back at the neonatal period in early-treated phenylketonuric patients

Vincenzo Leuzzi  1 , Francesca Nardecchia  2
Affiliations
Comment

Looking back at the neonatal period in early-treated phenylketonuric patients

Vincenzo Leuzzi et al. Pediatr Res. 2022 Mar.
No abstract available

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References

    1. Blau, N., van Spronsen, F. J. & Levy, H. L. Phenylketonuria. Lancet 376, 1417–1427 (2010). - DOI
    1. Smith, I., Beasley, M. G. & Ades, A. E. Intelligence and quality of dietary treatment in phenylketonuria. Arch. Dis. Child. 65, 472–478 (1990). - DOI
    1. Waisbren, S. E. et al. Phenylalanine blood levels and clinical outcomes in phenylketonuria: a systematic literature review and meta-analysis. Mol. Genet. Metab. 92, 63–70 (2007). - DOI
    1. Hofman, D. L., Champ, C. L., Lawton, C. L., Henderson, M. & Dye, L. A systematic review of cognitive functioning in early treated adults with phenylketonuria. Orphanet J. Rare Dis. 13, 150 (2018). - DOI
    1. Leuzzi, V., Chiarotti, F., Nardecchia, F., van Vliet, D. & van Spronsen, F. J. Predictability and inconsistencies of cognitive outcome in patients with phenylketonuria and personalised therapy: the challenge for the future guidelines. J. Med. Genet. 57, 145–150 (2020). - DOI

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