Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan 4:12:706275.
doi: 10.3389/fpsyt.2021.706275. eCollection 2021.

Characteristics of Obstructive Sleep Apnea Patients With Hypertension and Factors Associated With Autotitration Acceptance

Xuan Zhang  1   2 , Ning Zhang  2   3   4 , Yang Yang  2   3 , Shuo Wang  2   3 , Ping Yu  1   2 , Bo-Yuan Guan  2   3 , Chun-Xue Wang  2   3   4   5
Affiliations

Characteristics of Obstructive Sleep Apnea Patients With Hypertension and Factors Associated With Autotitration Acceptance

Xuan Zhang et al. Front Psychiatry. .

Abstract

In order to explore the characteristics and treatment status of obstructive sleep apnea (OSA) patients with hypertension, a retrospective study was conducted on 306 patients admitted from October 2018 to December 2019. According to the apnea hypopnea index (AHI), OSA patients with hypertension were divided into three groups. 69 cases were mild OSA (5 ≤ AHI < 15), 86 cases were moderate (15 ≤ AHI < 30), and 151 cases were severe (AHI ≥ 30). Compared with patients in the mild and moderate groups, the severe group had more male patients, with higher body mass index (BMI) and non-rapid eye movement stage 1 accounted for total sleep time (N1%), and lower non-rapid eye movement stage 2 accounted for total sleep time (N2%), average and minimum blood oxygen. Among all the patients, those who underwent the titration test accounted for 20.6% (63/306). Multivariate analysis showed that sleep efficiency (p < 0.001) and AHI (p < 0.001) were independent factors for patients to accept titration test. OSA patients with hypertension had a low acceptance of titration therapy. These people with higher sleep efficiency and AHI were more likely to receive autotitration.

Keywords: apnea hypopnea index; hypertension; obstructive sleep apnea; sleep efficiency; titration test.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Similar articles

See all similar articles

Cited by

References

    1. Drager LF, Genta PR, Pedrosa RP, Nerbass FB, Gonzaga CC, Krieger EM, et al. . Characteristics and predictors of obstructive sleep apnea in patients with systemic hypertension. Am J Cardiol. (2010) 105:1135–9. 10.1016/j.amjcard.2009.12.017 - DOI - PubMed
    1. Chobanian A, Bakris G, Black H, Cushman W, Green L, Izzo J, et al. . The Seventh Report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA. (2003) 289:2560–72. 10.1001/jama.289.19.2560 - DOI - PubMed
    1. Kiely J, McNicholas W. Cardiovascular risk factors in patients with obstructive sleep apnoea syndrome. Eur Respir J. (2000) 16:128–33. 10.1034/j.1399-3003.2000.16a23.x - DOI - PubMed
    1. Kraiczi H, Hedner J, Peker Y, Grote L. Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea. Am J Respir Crit Care Med. (2000) 161:1423–8. 10.1164/ajrccm.161.5.9909024 - DOI - PubMed
    1. Torres G. Sanchez-de-la-Torre M, Barbe F. Relationship between OSA and hypertension. Chest. (2015) 148:824–32. 10.1378/chest.15-0136 - DOI - PubMed

LinkOut - more resources