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Review
. 2022 Jan 4:12:820497.
doi: 10.3389/fpsyt.2021.820497. eCollection 2021.

Allergic Rhinitis and Depression: Profile and Proposal

Ya-Kui Mou  1   2 , Han-Rui Wang  1   2 , Wen-Bin Zhang  1   2 , Yu Zhang  1   2 , Chao Ren  1   2   3 , Xi-Cheng Song  1   2   3
Affiliations
Review

Allergic Rhinitis and Depression: Profile and Proposal

Ya-Kui Mou et al. Front Psychiatry. .

Abstract

In addition to nasal symptoms, patients with allergic rhinitis (AR) often experience mental and psychological disorders such as depression. Depression not only makes the treatment of AR more difficult and expensive but also poses a serious impact on the patients' daily activities and quality of life, thus bringing additional burden to the families and the society. Here we systematically review the recent research advances in the correlation between AR and depression, analyze the possible causes and mechanisms of depression in AR, summarize the current diagnosis and treatment strategies, and provide our insights into the AR-related depression; in addition, we introduce briefly the basic research status on AR-related depression. We hope that this review article will provide evidence for future studies.

Keywords: allergic rhinitis; brain; depression; immunity; inflammation.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Schematic diagram of the relationship between depression and AR.
Figure 2
Figure 2
Classification of depression in AR based on possible pathogenesis.
See this image and copyright information in PMC

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