Why stratification is important in primary Sjögren's syndrome

D W Lendrem^{1

2}, J R Tarn³, A Collins⁴, J Wason⁵, W F Ng^{3

6}

Affiliations

¹ Musculoskeletal Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle University, Tyne and Wear, Newcastle upon Tyne, UK. dennis.lendrem@ncl.ac.uk.
² NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne NHS Foundation Trust, Tyne and Wear, Newcastle upon Tyne, UK. dennis.lendrem@ncl.ac.uk.
³ Musculoskeletal Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle University, Tyne and Wear, Newcastle upon Tyne, UK.
⁴ Royal Brompton Hospital, Sydney Street, London, UK.
⁵ Faculty of Medical Sciences, Population Health Sciences Institute, Newcastle University, Tyne and Wear, Newcastle upon Tyne, UK.
⁶ NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne NHS Foundation Trust, Tyne and Wear, Newcastle upon Tyne, UK.

Comment

D W Lendrem et al. Rheumatol Int. 2022 Sep.

. 2022 Sep;42(9):1661-1662.

doi: 10.1007/s00296-021-05068-y. Epub 2022 Jan 20.

D W Lendrem^{1

2}, J R Tarn³, A Collins⁴, J Wason⁵, W F Ng^{3

6}

¹ Musculoskeletal Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle University, Tyne and Wear, Newcastle upon Tyne, UK. dennis.lendrem@ncl.ac.uk.
² NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne NHS Foundation Trust, Tyne and Wear, Newcastle upon Tyne, UK. dennis.lendrem@ncl.ac.uk.
³ Musculoskeletal Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle University, Tyne and Wear, Newcastle upon Tyne, UK.
⁴ Royal Brompton Hospital, Sydney Street, London, UK.
⁵ Faculty of Medical Sciences, Population Health Sciences Institute, Newcastle University, Tyne and Wear, Newcastle upon Tyne, UK.
⁶ NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne NHS Foundation Trust, Tyne and Wear, Newcastle upon Tyne, UK.

No abstract available

Comment on

Revisiting the JOQUER trial: stratification of primary Sjögren's syndrome and the clinical and interferon response to hydroxychloroquine.
Collins A, Lendrem D, Wason J, Tarn J, Howard-Tripp N, Bodewes I, Versnel MA, Gottenberg JE, Seror R, Mariette X, Ng WF. Collins A, et al. Rheumatol Int. 2021 Sep;41(9):1593-1600. doi: 10.1007/s00296-021-04927-y. Epub 2021 Jun 24. Rheumatol Int. 2021. PMID: 34165604 Free PMC article. Clinical Trial.
The stratification of primary Sjogren's syndrome: is it really solving the problem?
Baicus C. Baicus C. Rheumatol Int. 2021 Dec;41(12):2241. doi: 10.1007/s00296-021-04964-7. Epub 2021 Aug 11. Rheumatol Int. 2021. PMID: 34379178 No abstract available.

1. Baicus C (2021) The stratification of primary Sjogren’s syndrome: is it really solving the problem? Rheumatol Int 41(12):2241 - DOI
1. Collins A, Lendrem D, Wason J, Tarn J, Howard-Tripp N, Bodewes I, Versnel MA, Gottenberg JE, Seror R, Mariette X, Ng WF (2021) Revisiting the JOQUER trial: stratification of primary Sjögren’s syndrome and the clinical and interferon response to hydroxychloroquine. Rheumatol Int 41(9):1593–1600 - DOI
1. Tarn JR, Howard-Tripp N, Lendrem DW, Mariette X, Saraux A, Devauchelle-Pensec V, Seror R, Skelton AJ, James K, McMeekin P, Al-Ali S (2019) Symptom-based stratification of patients with primary Sjögren’s syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials. Lancet Rheumatol 1(2):e85-94 - DOI
1. Lee JJ, Park YJ, Park M, Yim HW, Park SH, Kwok SK (2021) Longitudinal analysis of symptom-based clustering in patients with primary Sjogren’s syndrome: a prospective cohort study with a 5-year follow-up period. J Transl Med 19(1):1–8 - DOI
1. Gottenberg JE, Ravaud P, Puéchal X, Le Guern V, Sibilia J, Goeb V, Larroche C, Dubost JJ, Rist S, Saraux A, Devauchelle-Pensec V (2014) Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial. JAMA 312(3):249–258 - DOI