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Review
. 2022 May;27(5):391-403.
doi: 10.1111/nep.14024. Epub 2022 Jan 31.

The case for increased peritoneal dialysis utilization in low- and lower-middle-income countries

Ikechi G Okpechi  1   2   3 , Vivekanand Jha  4   5   6 , Yeoungjee Cho  7   8   9 , Feng Ye  1 , Chukwuonye I Ijezie  10 , Kailash Jindal  1 , Scott Klarenbach  1 , Muhammad A Makusidi  11 , Ugochi S Okpechi-Samuel  12 , Chimezie Okwuonu  10 , Nikhil Shah  1 , Stephanie Thompson  1 , Marcello Tonelli  13 , David W Johnson  8   9   14 , Aminu K Bello  1
Affiliations
Review

The case for increased peritoneal dialysis utilization in low- and lower-middle-income countries

Ikechi G Okpechi et al. Nephrology (Carlton). 2022 May.

Abstract

Peritoneal dialysis (PD) has several advantages compared to haemodialysis (HD), but there is evidence showing underutilization globally, especially in low-income and lower-middle-income countries (LLMICs) where kidney replacement therapies (KRT) are often unavailable, inaccessible, and unaffordable. Only 11% of all dialysis patients worldwide use PD, more than 50% of whom live in China, the United States of America, Mexico, or Thailand. Various barriers to increased PD utilization have been reported worldwide including patient preference, low levels of education, and lower provider reimbursement. However, unique but surmountable barriers are applicable to LLMICs including the excessively high cost of providing PD (related to PD fluids in particular), excessive cost of treatment borne by patients (relative to HD), lack of adequate PD training opportunities for doctors and nurses, low workforce availability for kidney care, and challenges related to some PD outcomes (catheter-related infections, hospitalizations, mortality, etc.). This review discusses some known barriers to PD use in LLMICs and leverages data that show a global trend in reducing rates of PD-related infections, reducing rates of modality switches from HD, and improving patient survival in PD to discuss how PD use can be increased in LLMICs. We therefore, challenge the idea that low PD use in LLMICs is unavoidable due to these barriers and instead present opportunities to improve PD utilization in LLMICs.

Keywords: chronic kidney disease; cost; kidney outcomes; kidney replacement therapies; low-income and lower-middle-income countries; peritoneal dialysis.

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References

REFERENCES

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