Meta-Analysis of Risk of Myocarditis After Messenger RNA COVID-19 Vaccine

doi:10.1016/j.amjcard.2021.12.007

Meta-Analysis

. 2022 Mar 15:167:155-157.

doi: 10.1016/j.amjcard.2021.12.007. Epub 2022 Jan 19.

Meta-Analysis of Risk of Myocarditis After Messenger RNA COVID-19 Vaccine

Mingwei Wang¹, Wen Wen¹, Mengyun Zhou², Chunyi Wang¹, Zhan-Hui Feng³

Affiliations

¹ Hangzhou Institute of Cardiovascular Diseases, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
² Department of Molecular & Cellular Physiology, Shinshu University School of Medicine, Matsumoto, Japan.
³ Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.

PMID: 35063268
PMCID: PMC8767906
DOI: 10.1016/j.amjcard.2021.12.007

Meta-Analysis

Meta-Analysis of Risk of Myocarditis After Messenger RNA COVID-19 Vaccine

Mingwei Wang et al. Am J Cardiol. 2022.

. 2022 Mar 15:167:155-157.

doi: 10.1016/j.amjcard.2021.12.007. Epub 2022 Jan 19.

Authors

Mingwei Wang¹, Wen Wen¹, Mengyun Zhou², Chunyi Wang¹, Zhan-Hui Feng³

Affiliations

¹ Hangzhou Institute of Cardiovascular Diseases, Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
² Department of Molecular & Cellular Physiology, Shinshu University School of Medicine, Matsumoto, Japan.
³ Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.

PMID: 35063268
PMCID: PMC8767906
DOI: 10.1016/j.amjcard.2021.12.007

No abstract available

PubMed Disclaimer

Figures

**Figure 1**
Forest map: mRNA vaccine associated with myocarditis. CI = confidence interval; ES = Effect size.

See this image and copyright information in PMC

Cited by

Cardiac Safety of mRNA-Based Vaccines in Patients with Systemic Lupus Erythematosus and Lupus-like Disorders with a History of Myocarditis.
Ramirez GA, Batani V, Moroni L, De Luca G, Pizzetti G, Sala S, Peretto G, Campochiaro C, Della-Torre E, Bozzolo EP, Dagna L. Ramirez GA, et al. Pathogens. 2022 Sep 1;11(9):1001. doi: 10.3390/pathogens11091001. Pathogens. 2022. PMID: 36145434 Free PMC article.
Cardiovascular Sequelae of the COVID-19 Vaccines.
Nitz JN, Ruprecht KK, Henjum LJ, Matta AY, Shiferaw BT, Weber ZL, Jones JM, May R, Baio CJ, Fiala KJ, Abd-Elsayed AA. Nitz JN, et al. Cureus. 2025 Apr 10;17(4):e82041. doi: 10.7759/cureus.82041. eCollection 2025 Apr. Cureus. 2025. PMID: 40351947 Free PMC article. Review.
Incidence of Myocarditis after Messenger RNA Vaccine for COVID-19 in Young Male Recipients.
Kato S, Horita N, Utsunomiya D. Kato S, et al. Am J Cardiol. 2022 Jun 1;172:159-161. doi: 10.1016/j.amjcard.2022.02.010. Epub 2022 Mar 23. Am J Cardiol. 2022. PMID: 35339272 Free PMC article. No abstract available.
Overview of the cardio-metabolic impact of the COVID-19 pandemic.
Barkhordarian M, Behbood A, Ranjbar M, Rahimian Z, Prasad A. Barkhordarian M, et al. Endocrine. 2023 Jun;80(3):477-490. doi: 10.1007/s12020-023-03337-3. Epub 2023 Apr 27. Endocrine. 2023. PMID: 37103684 Free PMC article. Review.
COVID-19 pandemic and hypertension: an updated report from the Japanese Society of Hypertension project team on COVID-19.
Shibata S, Kobayashi K, Tanaka M, Asayama K, Yamamoto E, Nakagami H, Hoshide S, Kishi T, Matsumoto C, Mogi M, Morimoto S, Yamamoto K, Mukoyama M, Kario K, Node K, Rakugi H. Shibata S, et al. Hypertens Res. 2023 Mar;46(3):589-600. doi: 10.1038/s41440-022-01134-5. Epub 2022 Dec 23. Hypertens Res. 2023. PMID: 36550205 Free PMC article. Review.

See all "Cited by" articles

References

1. Hause AM, Gee J, Baggs J, Abara WE, Marquez P, Thompson D, Su JR, Licata C, Rosenblum HG, Myers TR, Shimabukuro TT, Shay DK. COVID-19 vaccine safety in adolescents aged 12-17 years - United States, December 14, 2020-July 16, 2021. MMWR Morb Mortal Wkly Rep. 2021;70:1053–1058. - PMC - PubMed
1. Mevorach D, Anis E, Cedar N, Bromberg M, Haas EJ, Nadir E, Olsha-Castell S, Arad D, Hasin T, Levi N, Asleh R, Amir O, Meir K, Cohen D, Dichtiar R, Novick D, Hershkovitz Y, Dagan R, Leitersdorf I, Ben-Ami R, Miskin I, Saliba W, Muhsen K, Levi Y, Green MS. Keinan-Boker L, Alroy-Preis S. Myocarditis after BNT162b2 mRNA vaccine against COVID-19 in Israel. N Engl J Med. 2021;385:2140–2149. - PMC - PubMed
1. Montgomery J, Ryan M, Engler R, Hoffman D, McClenathan B, Collins L, Loran D, Hrncir D, Herring K, Platzer M, Adams N, Sanou A, Cooper LT., Jr Myocarditis following immunization with mRNA COVID-19 vaccines in members of the US military. JAMA Cardiol. 2021;6:1202–1206. - PMC - PubMed
1. Diaz GA, Parsons GT, Gering SK, Meier AR, Hutchinson IV, Robicsek A. Myocarditis and pericarditis after vaccination for COVID-19. JAMA. 2021;326:1210–1212. - PMC - PubMed
1. Kim HW, Jenista ER, Wendell DC, Azevedo CF, Campbell MJ, Darty SN, Parker MA, Kim RJ. Patients with acute myocarditis following mRNA COVID-19 vaccination. JAMA Cardiol. 2021;6:1196–1201. - PMC - PubMed

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Medical
- MedlinePlus Health Information

[1] Hause AM, Gee J, Baggs J, Abara WE, Marquez P, Thompson D, Su JR, Licata C, Rosenblum HG, Myers TR, Shimabukuro TT, Shay DK. COVID-19 vaccine safety in adolescents aged 12-17 years - United States, December 14, 2020-July 16, 2021. MMWR Morb Mortal Wkly Rep. 2021;70:1053–1058. - PMC - PubMed

[2] Hause AM, Gee J, Baggs J, Abara WE, Marquez P, Thompson D, Su JR, Licata C, Rosenblum HG, Myers TR, Shimabukuro TT, Shay DK. COVID-19 vaccine safety in adolescents aged 12-17 years - United States, December 14, 2020-July 16, 2021. MMWR Morb Mortal Wkly Rep. 2021;70:1053–1058. - PMC - PubMed

[3] Mevorach D, Anis E, Cedar N, Bromberg M, Haas EJ, Nadir E, Olsha-Castell S, Arad D, Hasin T, Levi N, Asleh R, Amir O, Meir K, Cohen D, Dichtiar R, Novick D, Hershkovitz Y, Dagan R, Leitersdorf I, Ben-Ami R, Miskin I, Saliba W, Muhsen K, Levi Y, Green MS. Keinan-Boker L, Alroy-Preis S. Myocarditis after BNT162b2 mRNA vaccine against COVID-19 in Israel. N Engl J Med. 2021;385:2140–2149. - PMC - PubMed

[4] Mevorach D, Anis E, Cedar N, Bromberg M, Haas EJ, Nadir E, Olsha-Castell S, Arad D, Hasin T, Levi N, Asleh R, Amir O, Meir K, Cohen D, Dichtiar R, Novick D, Hershkovitz Y, Dagan R, Leitersdorf I, Ben-Ami R, Miskin I, Saliba W, Muhsen K, Levi Y, Green MS. Keinan-Boker L, Alroy-Preis S. Myocarditis after BNT162b2 mRNA vaccine against COVID-19 in Israel. N Engl J Med. 2021;385:2140–2149. - PMC - PubMed

[5] Montgomery J, Ryan M, Engler R, Hoffman D, McClenathan B, Collins L, Loran D, Hrncir D, Herring K, Platzer M, Adams N, Sanou A, Cooper LT., Jr Myocarditis following immunization with mRNA COVID-19 vaccines in members of the US military. JAMA Cardiol. 2021;6:1202–1206. - PMC - PubMed

[6] Montgomery J, Ryan M, Engler R, Hoffman D, McClenathan B, Collins L, Loran D, Hrncir D, Herring K, Platzer M, Adams N, Sanou A, Cooper LT., Jr Myocarditis following immunization with mRNA COVID-19 vaccines in members of the US military. JAMA Cardiol. 2021;6:1202–1206. - PMC - PubMed

[7] Diaz GA, Parsons GT, Gering SK, Meier AR, Hutchinson IV, Robicsek A. Myocarditis and pericarditis after vaccination for COVID-19. JAMA. 2021;326:1210–1212. - PMC - PubMed

[8] Diaz GA, Parsons GT, Gering SK, Meier AR, Hutchinson IV, Robicsek A. Myocarditis and pericarditis after vaccination for COVID-19. JAMA. 2021;326:1210–1212. - PMC - PubMed

[9] Kim HW, Jenista ER, Wendell DC, Azevedo CF, Campbell MJ, Darty SN, Parker MA, Kim RJ. Patients with acute myocarditis following mRNA COVID-19 vaccination. JAMA Cardiol. 2021;6:1196–1201. - PMC - PubMed

[10] Kim HW, Jenista ER, Wendell DC, Azevedo CF, Campbell MJ, Darty SN, Parker MA, Kim RJ. Patients with acute myocarditis following mRNA COVID-19 vaccination. JAMA Cardiol. 2021;6:1196–1201. - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Meta-Analysis of Risk of Myocarditis After Messenger RNA COVID-19 Vaccine

Affiliations

Meta-Analysis of Risk of Myocarditis After Messenger RNA COVID-19 Vaccine

Authors

Affiliations

Figures

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Figures

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources

Medical