Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 May;42(4):859-861.
doi: 10.1007/s10875-021-01192-3. Epub 2022 Jan 22.

Fatal and Unresponsive Cytomegalovirus Infection in a New Homozygous FOXN1 Gene Variation Causing Nude SCID

Collaborators, Affiliations

Fatal and Unresponsive Cytomegalovirus Infection in a New Homozygous FOXN1 Gene Variation Causing Nude SCID

Herberto Jose Chong-Neto et al. J Clin Immunol. 2022 May.

Erratum in

No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Alopecia universalis in a nude SCID infant
Fig. 2
Fig. 2
Nail dystrophy in a nude SCID infant
Fig. 3
Fig. 3
A family pedigree with the segregation of the FOXN1 mutation

References

    1. Tangye SG, Al-Herz W, Bousfiha A, Chatila T, Cunningham- Rundles C, Etzioni A, et al. Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee. J Clin Immunol. 2020;40:24–64. doi: 10.1007/s10875-019-00737-x. - DOI - PMC - PubMed
    1. Bousfiha A, Jeddane L, Picard C, Al-Herz W, Ailal F, Chatila T, et al. Human inborn errors of immunity: 2019 update of the IUIS phenotypical classification. J Clin Immunol. 2020;40:66–81. doi: 10.1007/s10875-020-00758-x. - DOI - PMC - PubMed
    1. Fischer A, Notarangelo LD, Neven B, Cavazzana M, Puck JM. Severe combined immunodeficiencies and related disorders. Nat Rev Dis Primers. 2015;1:15061. doi: 10.1038/nrdp.2015.61. - DOI - PubMed
    1. Gallo V, Cirillo E, Giardino G, Pignata C. FOXN1 deficiency: from the discovery to novel therapeutic approaches. J Clin Immunol. 2017;37:751–758. doi: 10.1007/s10875-017-0445-z. - DOI - PubMed
    1. Giardino G, Sharapova SO, Ciznar P, Dhala F, Maragliano L, Rama AR, et al. Expanding the nude SCID/CID phenotype associated with FOXN1 homozygous, compound heterozygous, or heterozygous mutations. J Clin Immunol. 2021;41:756–768. doi: 10.1007/s10875-021-00967-y. - DOI - PMC - PubMed

Publication types

Substances