PNT declares grants from the National Institute on Aging (NIA; RF1 AG041705, 1UF1AG046150, R01 AG031581, R01 AG055444, P30 AG19610); consulting fees from Acadia, Biogen, Genentech, and Novo Nordisk; speakers fees from Clinical Care and WebMD; travel fees from the Alzheimer's Clinical Trials Consortium Alzheimer's Therapeutic Research Institute, Acadia, Cortexyme, and Gerontological Society of America; advisory board or data safety monitoring board membership for Abbvie, AC Immune, Axsome, BioXcel, Cortexyme, Eisai, Genentech, Eisai, Merck, Otuska & Astex, T3D Therapeutics, and Syneos; shares in Adamas Pharmaceuticals (sold in December 2020); and a contribution to a patent (11/632,747) with the University of Rochester. CB declares consulting fees from Acadia, AARP, Addex, Biohaven, Eli Lily, Enterin, Exciva, H Lundbeck, Janssen Pharmaceuticals, Novo Nordisk, Orion, Otsuka America Pharm, Sunovion Pharm, Suven, Roche, Axosome, and Biogen; speakers fees from Harvard University; travel fees from AARP and Acadia; and advisory board membership for Acadia, Roche, Novo-Nordisk, AARP, Biogen, and Synexus. DPD declares grants from the NIA and Alzheimer's Association; and consulting fees from Acadia, Eisai, Genentech, Novo Nordisk, Jazz Pharmaceuticals, and Biogen. JLC declares grants from the National Institute of General Medical Sciences (P20GM109025), the National Institute of Neurological Disorders and Stroke (U01NS093334), the NIA (R01AG053798, P20AG068053, R35AG71476), and the Alzheimer's Disease Drug Discovery Foundation; royalties from the Neuropsychiatric Inventory; consulting fees from AB Science, Acadia, Alkahest, AlphaCognition, ALZPathFinder, Annovis, AriBio, Artery, Avanir, Biogen, Biosplice, Cassava, Cerevel, Clinilabs, Cortexyme, Diadem, EIP Pharma, Eisai, GatehouseBio, GemVax, Genentech, Green Valley, Grifols, Janssen, Karuna, Lexeo, Lilly, Lundbeck, LSP, Merck, NervGen, Novo Nordisk, Oligomerix, Ono, Otsuka, PharmacotrophiX, PRODEO, Prothena, ReMYND, Renew, Resverlogix, Roche, Signant Health, Suven, Unlearn AI, Vaxxinity, and VigilNeuro; speakers fees from Eisai; and advisory board or data safety monitoring board membership for Acadia, Biogen, Eisai, Genentech, Green Valley, Karuna, Lilly, Lundbeck, Merck, NervGen, Novo Nordisk, Otsuka, Roche, Signant Health, and Vaxxinity. DLS declares research support to his institution from Eisai; consulting fees from Avanir; and advisory board membership, data safety monitoring board membership, or study adjudication committee membership for Acadia, Avanir, Janssen, Otsuka, Aptinyx, and NovoNordisk.