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. 2022 Jan 24;13(1):14.
doi: 10.1186/s13244-021-01149-5.

Computed tomography features and clinical characteristics of gastritis cystica profunda

Rui Wang  1   2 , Hao Lu  1   2 , Juan Yu  1   2 , Wenpeng Huang  1   2 , Jing Li  3 , Ming Cheng  4 , Pan Liang  1   2 , Liming Li  1   2 , Huiping Zhao  1   2 , Jianbo Gao  5   6
Affiliations

Computed tomography features and clinical characteristics of gastritis cystica profunda

Rui Wang et al. Insights Imaging. .

Abstract

Background: The diagnostic evidence of gastritis cystica profunda (GCP) are not adequately described due to its extremely low morbidity. This study aimed to analyze and summarize the comprehensive CT features and clinical characteristics of patients with GCP.

Results: Nineteen patients were enrolled, including eight men and eleven women, with a mean age of 55.53 years. Only one patient had the history of gastric polypectomy. Among the nineteen cases, two cases were in the gastric cardia, four in the gastric fundus, eight in the gastric body and five in the gastric antrum. The shapes were sphere in thirteen patients, hemisphere in five patients and diffuse in one patient. The mean size of eighteen local lesions was 1.63 cm. The cystic changes in submucosa were detected in fifteen patients. Compared with the pancreas, most GCP lesions were hypo-attenuated on unenhanced CT (n = 8), in arterial phase (AP) (n = 17) and venous phase (VP) (n = 11). Fifteen patients had the peak enhancement in VP and two in AP. The rim-like enhancement with central low attenuation was clearly observed in thirteen patients. For the GCP accompanied by adenocarcinoma, the enhancement peak was present in AP and the gradual expansion of enhancement area was in VP. All patients underwent surgical or endoscopic resection. Sixteen cases had remission of symptoms and no recurrence.

Conclusions: The careful analysis of CT features and clinical characteristics can provide support for deepening the understanding of the GCP. However, a more accurate diagnosis depends on histopathological features.

Keywords: Diagnosis; Gastritis cystica profunda; Stomach; Tomography (X-ray computed).

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Conflict of interest statement

The authors of this manuscript declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
54-year-old man with GCP showing the diffuse thickening of gastric wall. a Axial unenhanced image reveals the thickened gastric mucosal folds pervading the large areas of gastric body. b Coronal venous phase CT shows multiple cysts in the submucosal layer
Fig. 2
Fig. 2
55-year-old woman with GCP revealing a 2.7-cm spherical mass with pedicle. Axial venous phase (a) and sagittal venous phase (b) CT images show a heterogeneous enhanced mass in the greater curvature of gastric body, which is connected to a 2.35-cm pedicle
Fig. 3
Fig. 3
61-year-old woman with GCP showing a 3.3-cm cystic mass. Axial venous phase (a) and coronal venous phase (b) CT images show the cystic mass located in the gastric antrum. This lesion is featured as multiple cysts separated by fibrous
Fig. 4
Fig. 4
34-year-old man with GCP accompanied by adenocarcinoma. a Axial unenhanced CT reveals an iso-attenuating hemisphere mass (arrow) in the lesser curvature of gastric body. b Axial arterial phase CT shows the obvious rim-like enhancement with central low attenuation of this mass (arrow). c Axial venous phase CT shows mild enhanced mass (arrow). The enhancement area of this mass is gradually expanding compared to the rim-like enhancement in arterial phase
See this image and copyright information in PMC

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