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Comment
. 2022 Mar;32(3):223-224.
doi: 10.1038/s41422-022-00621-1.

An exercise infusion benefits brain function

Affiliations
Comment

An exercise infusion benefits brain function

Alejandro Pinto et al. Cell Res. 2022 Mar.
No abstract available

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Figures

Fig. 1
Fig. 1. Effects of runner plasma (RP) on neurogenesis, neuroinflammation and memory.
RP administration to sedentary control mice resulted in increased hippocampal neurogenesis and gliogenesis, improved memory retention, and enhanced expression of genes important for learning and memory in the hippocampus. Clusterin (CLU) in RP reduced hippocampal neuroinflammation and may mediate beneficial effects of RP for brain function.

Comment on

  • Exercise plasma boosts memory and dampens brain inflammation via clusterin.
    De Miguel Z, Khoury N, Betley MJ, Lehallier B, Willoughby D, Olsson N, Yang AC, Hahn O, Lu N, Vest RT, Bonanno LN, Yerra L, Zhang L, Saw NL, Fairchild JK, Lee D, Zhang H, McAlpine PL, Contrepois K, Shamloo M, Elias JE, Rando TA, Wyss-Coray T. De Miguel Z, et al. Nature. 2021 Dec;600(7889):494-499. doi: 10.1038/s41586-021-04183-x. Epub 2021 Dec 8. Nature. 2021. PMID: 34880498 Free PMC article.

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