Give genotype-guided dual antiplatelet therapy a second CHANCE

Affiliations

¹ Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.
² Pharmacology, Catholic University, Largo F. Vito 1, 00168 Rome, Italy.

Comment

Giovanna Liuzzo et al. Eur Heart J. 2022.

. 2022 Mar 7;43(10):938-939.

doi: 10.1093/eurheartj/ehac024.

¹ Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.
² Pharmacology, Catholic University, Largo F. Vito 1, 00168 Rome, Italy.

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Comment on

Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA.
Wang Y, Meng X, Wang A, Xie X, Pan Y, Johnston SC, Li H, Bath PM, Dong Q, Xu A, Jing J, Lin J, Niu S, Wang Y, Zhao X, Li Z, Jiang Y, Li W, Liu L, Xu J, Chang L, Wang L, Zhuang X, Zhao J, Feng Y, Man H, Li G, Wang B; CHANCE-2 Investigators. Wang Y, et al. N Engl J Med. 2021 Dec 30;385(27):2520-2530. doi: 10.1056/NEJMoa2111749. Epub 2021 Oct 28. N Engl J Med. 2021. PMID: 34708996 Clinical Trial.