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. 2022 Feb;28(2):432-435.
doi: 10.3201/eid2802.211788.

Neisseria gonorrhoeae FC428 Subclone, Vietnam, 2019-2020

Trang Minh Trinh, Tam Thi Nguyen, Thanh Viet Le, Trang Thu Nguyen, Dan Thi Ninh, Bao Hac Duong, Minh Van Nguyen, Thomas Kesteman, Lan Thi Pham, H Rogier van Doorn

Neisseria gonorrhoeae FC428 Subclone, Vietnam, 2019-2020

Trang Minh Trinh et al. Emerg Infect Dis. 2022 Feb.

Abstract

Among 114 clinical Neisseria gonorrhoeae isolates collected in Vietnam during 2019-2020, we detected 15 of subclone sequence type 13871 of the FC428 clonal complex. Fourteen sequence type 13871 isolates with mosaic penA allele 60.001 were ceftriaxone or cefixime nonsusceptible, and 3/14 were azithromycin nonsusceptible. Emergence of this subclone threatens treatment effectiveness.

Keywords: FC428 clone; Neisseria gonorrhoeae; Vietnam; antimicrobial resistance; bacteria; cephalosporin resistance; gonorrhea; multidrug resistance.

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Figures

Figure
Figure
Time-scaled Bayesian maximum clade credibility phylogenetic tree of Neisseria gonorrhoeae ST13871 (17 isolates) with date of collection and location of collected isolates, Vietnam, 2019–2020. Red diamonds show posterior probability >90%; internal node labels show estimated time to most recent common ancestor.
See this image and copyright information in PMC

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