Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec;22(2):147-162.
doi: 10.1017/S146625232100013X.

Necrotic enteritis in chickens: a review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination

Mohammadali Alizadeh  1 , Bahram Shojadoost  1 , Nitish Boodhoo  1 , Jake Astill  2 , Khaled Taha-Abdelaziz  3 , Douglas C Hodgins  1 , Raveendra R Kulkarni  4 , Shayan Sharif  1
Affiliations
Review

Necrotic enteritis in chickens: a review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination

Mohammadali Alizadeh et al. Anim Health Res Rev. 2021 Dec.

Abstract

Necrotic enteritis (NE), caused by Clostridium perfringens (CP), is one of the most common of poultry diseases, causing huge economic losses to the poultry industry. This review provides an overview of the pathogenesis of NE in chickens and of the interaction of CP with the host immune system. The roles of management, nutrition, probiotics, and vaccination in reducing the incidence and severity of NE in poultry flocks are also discussed.

Keywords: Chickens; Clostridium perfringens; immune response; necrotic enteritis; pathogenesis; probiotics; vaccination.

PubMed Disclaimer

Publication types

LinkOut - more resources