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Comment
. 2022 Jan 24;57(2):149-151.
doi: 10.1016/j.devcel.2022.01.001.

PIWI puts spermatogenesis in its place

Amanda G Charlesworth  1 , Volker Nitschko  1 , Mathias S Renaud  1 , Julie M Claycomb  2
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PIWI puts spermatogenesis in its place

Amanda G Charlesworth et al. Dev Cell. .
Free article

Abstract

In this issue of Developmental Cell, Cornes et al. show that piRNAs initiate transcriptional silencing of spermatogenesis genes in the C. elegans germline via an endogenous nuclear RNAi pathway. This silencing enables a timely transition from spermatogenesis to oogenesis during hermaphrodite development, thus promoting fertility.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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