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. 2022 Feb 3;185(3):416-418.
doi: 10.1016/j.cell.2021.12.034. Epub 2022 Jan 25.

Microbiome engineering: Taming the untractable

James W Marsh  1 , Ruth E Ley  2
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Microbiome engineering: Taming the untractable

James W Marsh et al. Cell. .
Free article

Abstract

In this issue of Cell, Jin et al. describe several innovative tools for microbiome engineering to enable in situ editing of complex communities. However, challenges remain to overcome the widespread genetic intractability of microbiome constituents.

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