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. 2022 Jan 18:16:145-152.
doi: 10.2147/OPTH.S347382. eCollection 2022.

The Vivity Extended Range of Vision IOL vs the PanOptix Trifocal, ReStor 2.5 Active Focus and ReStor 3.0 Multifocal Lenses: A Comparison of Patient Satisfaction, Visual Disturbances, and Spectacle Independence

John A Hovanesian  1 , Michael Jones  2 , Quentin Allen  3
Affiliations

The Vivity Extended Range of Vision IOL vs the PanOptix Trifocal, ReStor 2.5 Active Focus and ReStor 3.0 Multifocal Lenses: A Comparison of Patient Satisfaction, Visual Disturbances, and Spectacle Independence

John A Hovanesian et al. Clin Ophthalmol. .

Abstract

Purpose: To compare patient-reported outcomes (PROs) after intraocular lens (IOL) implantation with the AcrySof IQ Vivity IOL or Vivity Toric IOL to those achieved with other multifocal IOLs.

Patients and methods: Prospective, open-label, multicenter analysis of PROs, including spectacle independence, dysphotopsia, and overall satisfaction among patients who underwent cataract surgery at least 1 month previously with bilateral Vivity or Vivity Toric lenses (n=60). Results were compared to outcomes from two similar prospective studies of bilateral AcrySof IQ PanOptix or PanOptix Toric trifocal IOLs (n = 59), blended AcrySof ReSTOR 2.5/3.0 IOLs (n=72) or bilateral ReSTOR ActiveFocus 2.5 D IOLs with a mini-monovision target [n = 95]).

Results: Patients in the Vivity cohort were significantly less likely to notice glare and halo in dim light (85% "none" or "just a little") compared to PanOptix (69%, p<0.03), 2.5 mini-monovision (75%, p< 0.05) or 2.5/3.0 (71%, p< 0.05) patients. Complete spectacle independence for all visual activities combined (never need glasses) with Vivity was comparable to the mini-monovision and 2.5/3.0 groups (33%, 36%, and 31%, respectively) but significantly lower than in the PanOptix cohort (83%, p < 0.0001). Satisfaction was high across all groups. There were no statistically significant differences in best-corrected visual acuity, and no new safety concerns were reported.

Conclusion: The AcrySof IQ Vivity extended depth of focus IOL offers an expanded range of vision and better spectacle independence than has typically been achieved with traditional monofocal IOLs, with high rates of satisfaction and a favorable dysphotopsia profile compared to diffractive multifocal IOLs.

Keywords: cataract surgery; glare; multifocal intraocular lens; spectacle independence.

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Conflict of interest statement

Dr John A Hovanesian reports grants from Alcon, during the conduct of the study. Drs Michael Jones and Quentin Allen are consultants for Alcon. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
Responses to the question, “How much do you notice glare or halos around lights in dim light situation?” suggest that patients implanted with Vivity IOLs were significantly less likely to notice glare and halos more than “just a little” and significantly more likely not to notice these symptoms at all compared to all other IOL cohorts. (p<0.02 vs Panoptix, p<0.03 vs 2.5/3.0 and 2.5 mini-mono, Chi squared test).
Figure 2
Figure 2
Frequency of spectacle use.
Figure 3
Figure 3
Satisfaction ratings of the Vivity lens were similar to other lenses among patients responding “very satisfied” or “satisfied”. Significantly more patients responded “very satisfied” to the Panoptix lens compared to all others.
Figure 4
Figure 4
All four groups had very good refractive accuracy. Compared to the Vivity, 2.5/3.0, and 2.5 mini-monovision cohorts, the PanOptix cohort had significantly higher refractive accuracy among patients within 0.25 and 0 diopters of emmetropia (P< 0.0001, chi-squared test for both groups).
None
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