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Review
. 2022 Jan 10:11:761521.
doi: 10.3389/fcimb.2021.761521. eCollection 2021.

Insights Into the Changing Landscape of Coronavirus Disease 2019

Ruby A Escobedo  1   2 , Deepak Kaushal  1 , Dhiraj K Singh  1
Affiliations
Review

Insights Into the Changing Landscape of Coronavirus Disease 2019

Ruby A Escobedo et al. Front Cell Infect Microbiol. .

Abstract

Coronavirus disease 2019 (COVID-19) is a highly contagious, infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in late 2019 in Wuhan China. A year after the World Health Organization declared COVID-19 a global pandemic, over 215 million confirmed cases and approximately 5 million deaths have been reported worldwide. In this multidisciplinary review, we summarize important insights for COVID-19, ranging from its origin, pathology, epidemiology, to clinical manifestations and treatment. More importantly, we also highlight the foundational connection between genetics and the development of personalized medicine and how these aspects have an impact on disease treatment and management in the dynamic landscape of this pandemic.

Keywords: COVID epidemiology; COVID origin; COVID treatment; COVID-19; SARS-CoV-2; coronavirus; targeted therapy.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Phylogenetic tree of SARS-CoV-2 and other related coronaviruses.
Figure 2
Figure 2
The rapid spread of COVID-19 worldwide.
See this image and copyright information in PMC

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