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. 2022 Apr;97(4):E159-E162.
doi: 10.1002/ajh.26479. Epub 2022 Feb 1.

TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia

Grégory Lazarian  1 , Floriane Theves  2 , Myriam Hormi  1 , Rémi Letestu  1 , Virginie Eclache  1 , Audrey Bidet  3 , Pascale Cornillet-Lefebvre  4 , Frédéric Davi  5 , Eric Delabesse  6 , Marie-Hélène Estienne  7 , Pascaline Etancelin  8 , Olivier Kosmider  9 , Sophy Laibe  10 , Laurence Lode  11 , Marc Muller  12 , Nathalie Nadal  13 , Dina Naguib  14 , Cédric Pastoret  15 , Stéphanie Poulain  16 , Pierre Sujobert  17 , Lauren Veronese  18 , Samia Imache  1 , Valérie Lefebvre  1 , Florence Cymbalista  1 , Fanny Baran-Marszak  1 , Thierry Soussi  19   20 ; French Innovative Leukemia Organisation (FILO)
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Free article

TP53 mutations at codon 234 are associated with chlorambucil treatment in chronic lymphocytic leukemia

Grégory Lazarian et al. Am J Hematol. 2022 Apr.
Free article
No abstract available

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References

REFERENCES

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    1. Doffe F, Carbonnier V, Tissier M, et al. Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene. Cell Death Differ. 2021;28(5):1477-1492. doi:10.1038/s41418-020-00672-0
    1. Soussi T, Leroy B, Devir M, Rosenberg S. High prevalence of cancer-associated TP53 variants in the gnomAD database: a word of caution concerning the use of variant filtering. Hum Mutat. 2019;40(5):516-524. doi:10.1002/humu.23717
    1. Canadillas JM, Tidow H, Freund SM, et al. Solution structure of p53 core domain: structural basis for its instability. Proc Natl Acad Sci U S A. 2006;103(7):2109-2114.
    1. Kotler E, Shani O, Goldfeld G, et al. A systematic p53 mutation library links differential functional impact to cancer mutation pattern and evolutionary conservation. Mol Cell. 2018;71(1):178-190.e8. doi:10.1016/j.molcel.2018.06.012

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