Increasing CART cell engine performance in CLL

Affiliations

¹ Cancer Center Amsterdam, Amsterdam Institute for Infection and Immunity, Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam University Medical Centers, University of Amsterdam.

Comment

Fleur S Peters et al. Blood. 2022.

. 2022 Jan 27;139(4):473-474.

doi: 10.1182/blood.2021013895.

¹ Cancer Center Amsterdam, Amsterdam Institute for Infection and Immunity, Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam University Medical Centers, University of Amsterdam.

No abstract available

Comment on

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity.
Funk CR, Wang S, Chen KZ, Waller A, Sharma A, Edgar CL, Gupta VA, Chandrakasan S, Zoine JT, Fedanov A, Raikar SS, Koff JL, Flowers CR, Coma S, Pachter JA, Ravindranathan S, Spencer HT, Shanmugam M, Waller EK. Funk CR, et al. Blood. 2022 Jan 27;139(4):523-537. doi: 10.1182/blood.2021011597. Blood. 2022. PMID: 35084470 Free PMC article.