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Review
. 2022 Mar:75:103293.
doi: 10.1016/j.amsu.2022.103293. Epub 2022 Jan 25.

SARS-CoV-2 vaccine-associated-tinnitus: A review

Syed Hassan Ahmed  1 , Summaiyya Waseem  1 , Taha Gul Shaikh  1 , Nashwa Abdul Qadir  1 , Sarush Ahmed Siddiqui  1 , Irfan Ullah  2 , Abdul Waris  2 , Zohaib Yousaf  3
Affiliations
Review

SARS-CoV-2 vaccine-associated-tinnitus: A review

Syed Hassan Ahmed et al. Ann Med Surg (Lond). 2022 Mar.

Abstract

The global vaccination drive against severe acute respiratory syndrome coronavirus-2 is being pursued at a historic pace. Unexpected adverse effects have been reported following vaccination, including thrombotic thrombocytopenia, myocarditis, amongst others. More recently, some cases of tinnitus are reported post-vaccination. According to the Vaccine Adverse Events Reporting System (VAERS), 12,247 cases of coronavirus post-vaccination tinnitus have been reported till September 14, 2021. To the best of our knowledge, this is the first review evaluating any otologic manifestation following vaccine administration and aims to evaluate the potential pathophysiology, clinical approach, and treatment. Although the incidence is infrequent, there is a need to understand the precise mechanisms and treatment for vaccine-associated-tinnitus.

Keywords: COVID-19; COVID-19 vaccine; Ear ringing; SARS-CoV-2; Tinnitus; Vaccine-associated tinnitus.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) flowchart.
Fig. 2
Fig. 2
Geographical distribution of reported cases.
See this image and copyright information in PMC

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