Disseminated Verruconis gallopava infection in a patient with systemic lupus erythematosus in Japan: A case report, literature review, and autopsy case

Abstract

Disseminated Verruconis gallopava infection is often reported in patients with severe immunodeficiency, such as those who have received an organ transplant or have hematological malignancies. The present report describes the first case of disseminated V. gallopava in a patient with systemic lupus erythematosus who used FK506 (Tacrolimus). In this case, β-D glucan was useful for diagnosis.

Keywords: Systemic lupus erythematosus; Verruconis gallopava.

Fig. 1

Computed tomography (CT) revealed a single nodule in his right lung(▶). Since it was a cavity lesion, we considered the possibility of fungal infection.

Fig. 2

This figure is CT images of the inguinal lesion. A: Axial section of CT. B: Coronal section of CT. A huge low density area with contrast effect was observed on the wall in the right iliopsoas muscle(▶).

Fig. 3

a. (left) Large colony (light olive green) grown on PDA (potato dextrose agar) at 28 °C on day 10 from a specimen obtained by a direct puncture. (right) The colony underside shows a reddish pigment. It has a two-celled cylindrical conidium at the tip. The shape of conidia is constricted at the septum. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)