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Case Reports
. 2022 May;111(5):1023-1026.
doi: 10.1111/apa.16276. Epub 2022 Feb 10.

Convulsions in children with COVID-19 during the Omicron wave

Jonas F Ludvigsson  1   2   3
Affiliations
Case Reports

Convulsions in children with COVID-19 during the Omicron wave

Jonas F Ludvigsson. Acta Paediatr. 2022 May.

Abstract

Aim: Most children with COVID-19 have mild symptoms, but data on the Omicron variant are rare. This paper describes unexpected cases with convulsions during 1 week in January 2022.

Methods: Four children with COVID-19 were admitted with convulsions to the paediatric department in Örebro, Sweden, when Omicron accounted for more than 98% of the country's COVID-19 cases. Three children tested positive for the virus, and one had clinical COVID-19. I was able to contact the parents of three boys, who gave consent for these case studies.

Results: Two boys aged 3 and 21 months tested positive for the virus and a 14-year-old boy tested negative, but had a cold and family members who had tested positive. The teenager had a history of urinary tract infections, but the younger boys had no earlier comorbidities. None had a history of epilepsy or febrile convulsions. The younger children had a fever and the teenager had upper respiratory symptoms. The 3-month-old child had repeated convulsions for several hours, the 21-month-old had continuous convulsions for 15-20 min, and the teenager had a convulsion for 30-60 s, followed by uncharacteristic aggression.

Conclusion: Convulsions may be a sign of the Omicron variant in children with COVID-19.

Keywords: COVID-19; Omicron; convulsions; pandemic; seizures.

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Conflict of interest statement

Dr Ludvigsson coordinated a study on behalf of the Swedish IBD quality register that received funding from Janssen Corporation.

Comment in

References

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Supplementary concepts