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Editorial
. 2022 May 4;24(5):708-710.
doi: 10.1093/neuonc/noac019.

Repurposing the drug verteporfin as anti-neoplastic therapy for glioblastoma

Renee D Read  1
Affiliations
Editorial

Repurposing the drug verteporfin as anti-neoplastic therapy for glioblastoma

Renee D Read. Neuro Oncol. .
No abstract available

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Figures

Fig. 1
Fig. 1
Schematic showing the effects of the drug verteporfin on glioblastoma. Created with Biorender.com.
See this image and copyright information in PMC

Comment on

References

    1. Tome-Garcia J, Erfani P, Nudelman G, et al. Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma. Nat Commun. 2018;9(1):4020. - PMC - PubMed
    1. Zheng Y, Pan D. The hippo signaling pathway in development and disease. Dev Cell. 2019;50(3):264–282. - PMC - PubMed
    1. Castellan M, Guarnieri A, Fujimura A, et al. Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in glioblastoma. Nat Cancer. 2021;2(2):174–188. - PMC - PubMed
    1. Vigneswaran K, Boyd NH, Oh SY, et al. YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma. Clin Cancer Res. 2021;27(5):1553–1569. - PMC - PubMed
    1. Gao M, Y F, Zhou W, et al. EGFR activates a TAZ-driven oncogenic program in glioblastoma. Cancer Res. 2021;81(13):3580–3592. - PMC - PubMed