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Comment
. 2022 Feb 8;119(6):e2120427119.
doi: 10.1073/pnas.2120427119.

Reply to Gaudry et al.: Cross-validation is necessary for the identification of pseudogenes

Yuan Yuan  1   2 , Inge Seim  3   4 , A Rus Hoelzel  5 , Yaolei Zhang  6   7   8 , Peijun Zhang  1 , Hui Kang  1 , Ding Wang  9 , Guangyi Fan  6   7   10 , Kun Wang  11 , Songhai Li  12   13
Affiliations
Comment

Reply to Gaudry et al.: Cross-validation is necessary for the identification of pseudogenes

Yuan Yuan et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no competing interest.

Figures

Fig. 1.
Fig. 1.
Differences in exon 1 and exon 6 sequences of UCP1 in Antarctic fur seal PacBio and Illumina genome assemblies. Gray blocks indicate regions unique to the Antarctic fur seal PacBio assembly. For comparison, the sequences of northern fur seal, walrus, and California sea lion are shown.
Fig. 2.
Fig. 2.
(A) Alignment of exon 1 and exon 3 of the UCP1 of southern elephant seal and northern elephant seal. The gray blocks and the red arrows show the position of the start codon, and the yellow blocks indicate amino acids missing in the elephant seals. (B) Summary of relaxed selection test of northern and southern elephant seal UCP1. A red star indicates the foreground branch.
See this image and copyright information in PMC

Comment on

References

    1. Yuan Y., et al. , Comparative genomics provides insights into the aquatic adaptations of mammals. Proc. Natl. Acad. Sci. U.S.A. 118, e2106080118 (2021). - PMC - PubMed
    1. Gaudry M. J., Fyda T. J., Jastroch M., Evolution of pinniped UCP1 is not linked to aquatic life but to neonatal thermogenesis and body size. Proc. Natl. Acad. Sci. U.S.A., 10.1073/pnas.2118431119 (2021). - DOI - PMC - PubMed
    1. Humble E., et al. , RAD sequencing and a hybrid Antarctic fur seal genome assembly reveal rapidly decaying linkage disequilibrium, global population structure and evidence for inbreeding. G3 (Bethesda) 8, 2709–2722 (2018). - PMC - PubMed
    1. Humble E., et al. , A draft fur seal genome provides insights into factors affecting SNP validation and how to mitigate them. Mol. Ecol. Resour. 16, 909–921 (2016). - PubMed

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