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. 2022 Feb 1;327(5):483-485.
doi: 10.1001/jama.2021.23652.

Trends in Use of Melatonin Supplements Among US Adults, 1999-2018

Jingen Li  1 , Virend K Somers  2 , Hao Xu  3 , Francisco Lopez-Jimenez  2 , Naima Covassin  2
Affiliations

Trends in Use of Melatonin Supplements Among US Adults, 1999-2018

Jingen Li et al. JAMA. .

Abstract

This study examines reported prevalence and trends in use of melatonin supplements among US adults from 1999 through 2018.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Somers reported having served as a consultant for Respicardia, Baker Tilly, Bayer, and Jazz Pharmaceuticals and serving on the Sleep Number Research Advisory Board. No other disclosures were reported.

Figures

Figure.
Figure.. Trends in Reported Weighted Prevalence of Overall Melatonin Use and Melatonin Use Greater Than 5 mg/d Among US Adults
The unweighted numbers of participants using melatonin overall and using >5 mg/d of melatonin were 296 and 39, respectively. Shaded areas indicate 95% confidence intervals. P values for linear and quadratic trends were calculated using linear regression modeling survey cycle as a continuous variable. For overall use, linear P = .004 and quadratic P < .001; for use greater than 5 mg/d, linear P = .005 and quadratic P = .04. Prevalence trends for melatonin use greater than 5 mg/d were estimated from the 2005-2006 to 2017-2018 cycles.
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