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Case Reports
. 1986 Mar 1;21(1):85-91.
doi: 10.1016/0165-4608(86)90203-7.

Chromosomal changes in a documented case of malignant histiocytosis: significance of polyploidy

J R Teyssier, C Behar, B Pignon, T Caulet, M Patey, F Bajolle, J J Adnet
Case Reports

Chromosomal changes in a documented case of malignant histiocytosis: significance of polyploidy

J R Teyssier et al. Cancer Genet Cytogenet. .

Abstract

A case of malignant histiocytosis was studied by cytology, cytochemistry, electron microscopy, and cytogenetics. It was shown that the malignant cells expressed a fully differentiated histiocytic pattern with high macrophagic activity. This correlated with the presence of polyploid metaphases. The significance of polyploid cells in the definition of malignant histiocytosis is discussed.

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