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. 2022 May;69(5):e29546.
doi: 10.1002/pbc.29546. Epub 2022 Feb 2.

Social determinants of health and pediatric cancer survival: A systematic review

Yvette H Tran  1   2 , Scott L Coven  3   4 , Seho Park  5   2 , Eneida A Mendonca  3   5   2
Affiliations

Social determinants of health and pediatric cancer survival: A systematic review

Yvette H Tran et al. Pediatr Blood Cancer. 2022 May.

Abstract

Despite treatment advancements and improved survival, approximately 1800 children in the United States will die of cancer annually. Survival may depend on nonclinical factors, such as economic stability, neighborhood and built environment, health and health care, social and community context, and education, otherwise known as social determinants of health (SDoH). Extant literature reviews have linked socioeconomic status (SES) and race to disparate outcomes; however, these are not inclusive of all SDoH. Thus, we conducted a systematic review on associations between SDoH and survival in pediatric cancer patients. Of the 854 identified studies, 25 were included in this review. In addition to SES, poverty and insurance coverage were associated with survival. More studies that include other SDoH, such as social and community factors, utilize prospective designs, and conduct analyses with more precise SDoH measures are needed.

Keywords: adolescents; cancer health disparities; childhood cancer; pediatrics; social determinants of health; survival.

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Conflict of interest statement

CONFLICT OF INTEREST

The authors declare that there is no conflict of interest.

Figures

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FIGURE 1
Process for eligible article inclusion
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