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. 2021 Nov-Dec;14(6):752-756.
doi: 10.5005/jp-journals-10005-2076.

Comparative Evaluation of Effect of Potassium Iodide and Glutathione on Tooth Discoloration after Application of 38% Silver Diamine Fluoride in Primary Molars: An In Vitro Study

Aishwarya N Kamble  1 , Vamsi K Chimata  1 , Farhin A Katge  1 , Komal K Nanavati  1 , Shilpa K Shetty  1
Affiliations

Comparative Evaluation of Effect of Potassium Iodide and Glutathione on Tooth Discoloration after Application of 38% Silver Diamine Fluoride in Primary Molars: An In Vitro Study

Aishwarya N Kamble et al. Int J Clin Pediatr Dent. 2021 Nov-Dec.

Abstract

Aim: To evaluate and compare the effect of potassium iodide (KI) and glutathione (GSH) on tooth discoloration after application of 38% silver diamine fluoride (SDF) in primary molars.Method: Total of 30 primary molars were randomly divided into three groups of 10 each. Teeth were prepared and divided into: Group A-SDF only, Group B-SDF followed immediately by application of KI, and Group C-SDF was mixed with 25 mg of GSH. Final restoration was done using glass ionomer cement. Visual examination and color assessments using spectrophotometer were recorded at three time interval points, that is, day 1, 1 week, and 4 weeks.

Results: Statistical analysis was done using a repeated measures analysis of variances (ANOVA) test. The spectrophotometer results showed that Group A (SDF) exhibited the greatest amount of discoloration at all time intervals, while Group C (SDF + GSH) group was effective in decreasing the discoloration. Whereas, Group B (SDF + KI) significantly reduced the discoloration over the period of time. (p = 0.008).

Conclusion: KI can effectively reduce discoloration after application of 38% SDF. GSH can also be used as an alternative.

Clinical significance: This two-step treatment for arresting caries can be a practical and low-cost option in areas with limited access to comprehensive dental care.

How to cite this article: Kamble AN, Chimata VK, Katge F A, et al. Comparative Evaluation of Effect of Potassium Iodide and Glutathione on Tooth Discoloration after Application of 38% Silver Diamine Fluoride in Primary Molars: An In Vitro Study. Int J Clin Pediatr Dent 2021;14(6):752-756.

Keywords: Glutathione; Potassium iodide; Silver diamine fluoride; Spectrophotometer; Tooth discoloration.

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Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Fig. 1
Fig. 1
Silver diamine fluoride (SDF) immediately followed by application of potassium iodide (KI)
Fig. 2
Fig. 2
A mixture of silver diamine fluoride (SDF) and glutathione (GSH) applied on prepared tooth surface
Fig. 3
Fig. 3
Bar chart showing mean and SD for ∆E for different tested groups at all the time interval points
Fig. 4
Fig. 4
Visual examination at all the time interval points
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