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Case Reports
. 2022 Jan 20:25:101308.
doi: 10.1016/j.ajoc.2022.101308. eCollection 2022 Mar.

Isolated hemangiopericytoma of the conjunctiva

William Edwards  1 , Caroline Craven  2 , Joseph Ryan Turner  1 , Hans Grossniklaus  2 , Jill Wells  2
Affiliations
Case Reports

Isolated hemangiopericytoma of the conjunctiva

William Edwards et al. Am J Ophthalmol Case Rep. .

Abstract

Purpose: To report a unique presentation of hemangiopericytoma and discuss the clinical course, pathological features, and management of this tumor.

Observations: An otherwise healthy 54-year-old Caucasian female presented with a painless conjunctival mass. The lesion gradually enlarged over a three-week period and was unresponsive to corticosteroid treatment. The mass was surgically removed, and histopathologic findings were consistent with hemangiopericytoma.

Conclusions and importance: Conjunctival hemangiopericytoma should be considered in patients with conjunctival lesions unresponsive to medical management. Surgical excision is diagnostic and therapeutic and is the strongest predictor of clinical course. Incompletely excised lesions are at a greater risk of local recurrence and subsequent metastasis. Given the neoplasm's malignant potential, patients should be followed in the outpatient setting.

Keywords: Conjunctiva; Hemangiopericytoma; Tumor.

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Conflict of interest statement

The following authors have no financial disclosures: WE, CC, JRT, HG, JW.

Figures

Fig. 1
Fig. 1
Patient at presentation with inferior bulbar conjunctiva lesion.
Fig. 2a
Fig. 2a
Spindle-shaped cells arranged in sheets (hematoxylin-eosin, magnification 25x).
Fig. 2b
Fig. 2b
Immunoperoxidase stain CD31 stains vascular channels, demonstrating a staghorn pattern (Immunoperoxidase stain CD 31, magnification x 100).
See this image and copyright information in PMC

References

    1. Enzinger F.M., Smith B.H. Hemangiopericytoma; an analysis of 106 cases. Hum Pathol. 1976;7:61–82. - PubMed
    1. Sujatha S., Sampath R., Bonshek R.E., Tullo A.B. Conjunctival haemangiopericytoma. Br J Ophthalmol. 1994;78:497–499. - PMC - PubMed
    1. Searl S., Ni C. Hemangiopericytoma. Int Ophthalmol Clin. 1982;22:141–162. - PubMed
    1. Grossniklaus H.E., Green W.R., Wolff S.M., Lliff N.T. Hemangiopericytoma of the conjunctiva: two cases. Ophthalmology. 1986;93:265–267. - PubMed
    1. Setzkorn R.K., Lee D., Lliff N.T., Green W.R. Hemangiopericytoma of the orbit treated with conservative surgery and radiotherapy. Arch Ophthalmol. 1987;105:1103–1105. - PubMed

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