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Randomized Controlled Trial
. 2022 Jun;407(4):1693-1700.
doi: 10.1007/s00423-022-02458-z. Epub 2022 Feb 3.

Sexual and functional outcomes after prolapse surgery: a randomized prospective comparison of trocarless transvaginal mesh and pelvic organ prolapse suspension

Andrea Fuschi  1   2 , Alessia Martoccia  1 , Yazan Al Salhi  1   2 , Martina Maggi  1   3 , Lorenzo Capone  1 , Paolo Pietro Suraci  1 , Alice Antonioni  1 , Giorgio Bozzini  4 , Ester Illiano  5 , Elisabetta Costantini  5 , Alessandro Zucchi  6 , Mauro Cervigni  1   2 , Antonio Carbone  1 , Antonio Luigi Pastore  7
Affiliations
Randomized Controlled Trial

Sexual and functional outcomes after prolapse surgery: a randomized prospective comparison of trocarless transvaginal mesh and pelvic organ prolapse suspension

Andrea Fuschi et al. Langenbecks Arch Surg. 2022 Jun.

Abstract

Purpose: Stress urinary incontinence (SUI) related to pelvic organ prolapse represents a common condition that negatively impacts female sexual activity. Laparoscopic pelvic organ prolapse surgery (POPs) and the anterior repair with a trocar-less trans-vaginal mesh (TTMs) represent two different surgical techniques to treat SUI secondary to POP. This study aimed to report the results of these techniques comparing the sexual and functional outcome improvement.

Materials and methods: Fifty-nine sexually active female patients, complaining of urodynamic stress incontinence, were enrolled in this prospective study, and simply randomized in two groups: 29 POPs and 30 TTMs. All patients were studied at baseline and 6 months after surgery. Preoperative evaluation included medical history, urodynamic test, Female Sexual Function Index (FSFI), and pelvic magnetic resonance defecography. Six months after surgery, all patients completed the FSFI and the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and were investigated with a uroflowmetry test with post-void residual volume (PVR).

Results: At 6 months after surgery, 87% of POPs patients and 79% of TTMs subjects resulted dry. No statistically significant results were obtained in terms of urinary outcomes between the two surgical groups. Regarding sexual function, POPs group exhibited a significant greater improvement of global FSFI (mean: 27.4; SD: 4.31) compared to TTMs group (mean FSFI: 23.56; SD: 2.28; p-value ≤ 0.0001).

Conclusions: Our results indicated that POPs and TTMs lead to satisfactory and safe functional outcomes with a good recovery of urinary continence. Furthermore, POPs, when compared to TTMs, led to a greater improvement of sexual function.

Keywords: Laparoscopy; Minimally invasive surgery; Pelvic organ prolapse; Sexual function; Trans-vaginal mesh; Urinary outcomes.

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